Sökning: "human monocytes"
Visar resultat 1 - 5 av 200 avhandlingar innehållade orden human monocytes.
1. Studies of prostaglandin E2 formationin human monocytes
Sammanfattning : Prostaglandin (PG) E2 is an eicosanoid derived from the polyunsaturated twenty carbon fatty acid arachidonic acid (AA). PGE2 has physiological as well as pathophysiological functions and is known to be a key mediator of inflammatory responses. LÄS MER
2. Human Forkhead Genes
Sammanfattning : The forkhead family constitutes a group of genes which encodes transcription factors that share a common DNA-binding domain, the forkhead domain. The first member to be discovered was the Drosophila melanogaster gene fork head. Members of this family have been found in a variety of species from bakers' yeast to man. LÄS MER
3. Human mononuclear phagocytes : Production of reactive oxygen species generated by the NADPH oxidase
Sammanfattning : Human professional phagocytes constitute the first line of defence against invading microorganisms. With a membrane-bound enzyme system, the NADPH oxidase, these cells generate bactericidal metabolites. Activation of NADPH oxidase results in a generation of reactive oxygen species, e.g. LÄS MER
4. Human dendritic cells : a study of early events during pathogen recognition and antigen endocytosis
Sammanfattning : The mononuclear phagocyte cell system includes monocytes, macrophages anddendritic cells which are important cells in order to recognize, ingest, destroyand also present part of a pathogen to T-lymphocytes in order to activate theadaptive immune system. Dendritic cells (DCs) stand out in their ability tostimulate T-lymphocytes and are also believed to be important to keeptolerance for “self-antigens”. LÄS MER
5. Monocytes and macrophages, with a focus of Crohn's disease
Sammanfattning : Monocytes and macrophages are part of the body’s first line of defense, eliminating pathogens by phagocytosis or by releasing a broad array of inflammatory mediators, such as cytokines, chemokines and proteases. In humans, three subsets of monocytes are described with seemingly different functions. LÄS MER