Sökning: "genome-wide studies"
Visar resultat 1 - 5 av 303 avhandlingar innehållade orden genome-wide studies.
1. Statistical Methods for Genome Wide Association Studies
Sammanfattning : This thesis focus on various statistical methods for analyzing Genome Wide Association data. The thesis include four papers, three of them considers the analysis of complex traits, and the last one a method for analyzing mendelian traits. LÄS MER
2. Genome-Wide Studies of Transcriptional Regulation in Mammalian Cells
Sammanfattning : The key to the complexity of higher organisms lies not in the number of protein coding genes they carry, but rather in the intrinsic complexity of the gene regulatory networks. The major effectors of transcriptional regulation are proteins called transcription factors, and in this thesis four papers describing genome-wide studies of seven such factors are presented, together with studies on components of the chromatin and transcriptome. LÄS MER
3. Theoretical studies of Membrane Proteins : Properties, Prediction Methods and Genome-wide analysis
Sammanfattning : Membrane proteins are a large and important class of proteins. They are responsible for several of the key functions in a living cell, e.g. transport of nutrients and ions, cell-cell signaling, and cell-cell adhesion. LÄS MER
4. Genome-Wide Studies of Transcriptional Regulation in Human Liver Cells by High-throughput Sequencing
Sammanfattning : The human genome contains slightly more than 20 000 genes that are expressed in a tissue specific manner. Transcription factors play a key role in gene regulation. By mapping the transcription factor binding sites genome-wide we can understand their role in different biological processes. LÄS MER
5. Improving methods for Genome Wide Analysis of Coeliac Disease
Sammanfattning : .... LÄS MER