Sökning: "focus on parkinson´s disease"

Hittade 5 avhandlingar innehållade orden focus on parkinson´s disease.

1. 1. Wearable sensors for monitoring epilepsy and Parkinson´s disease

   Författare :Dongni Johansson; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Epilepsy; Parkinson’s disease; Wearable sensors; Continuous and objective monitoring; End users’ perceptions; Qualitative content analysis; Machine learning algorithms; Tonic-clonic seizure detection; Dose titration; Motor state recognition;

   Sammanfattning : Introduction: Epilepsy and Parkinson’s disease (PD) are conditions where management would benefit greatly from monitoring symptoms over longer time periods in natural everyday environments instead of only intermittent assessments at clinics. Wearable technology with built-in sensors such as accelerometers and gyroscopes, could allow continuous and objective long-term monitoring of movement patterns. LÄS MER

3. 2. Cognitive effects of deep brain stimulation : focus on caudal zona incerta for essential tremor and Parkinson´s disease, and on bed nucleus of stria terminalis for obsessive compulsive disorder

   Författare :Johanna Philipson; Patric Blomstedt; Marjan Jahanshahi; Marwan Hariz; Jean-Luc Houéto; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Deep brain stimulation. Neuropsychology. Cognition. Parkinson’s disease. Essential tremor. Obsessive-compulsive disorder. Caudal zona incerta. Bed nucleus of stria terminalis. Functional MRI.; Neurology; neurologi;

   Sammanfattning : Preserved cognition is an important determinant for perceived Quality of Life (QoL) and has been found to be essential in order to translate improvements in primary symptoms following Deep Brain Stimulation (DBS) into activities of daily living that drive QoL. Therefore, it is important to evaluate not only the clinical improvement, but also the cognitive impact of DBS. LÄS MER

4. 3. Wnts in development : focus on midbrain

   Författare :Emma Rakel Andersson; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Studies in the field of embryonic development reveal the temporal and spatial requirement of specific genes/proteins in the formation of a given tissue. The specific knowledge of which genes/proteins regulate development of the ventral midbrain (VM) provides a guideline for the in vitro differentiation of specific cell types therein, such as dopaminergic (DA) neurons. LÄS MER

5. 4. Genetic variation in genes involved in Abeta-degradation in Alzheimer disease

   Författare :Mia Blomqvist; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Alzheimer disease; SNPs; genotyping; association study; haplotype; linkage disequilibrium; association mapping;

   Sammanfattning : Alzheimer disease (AD) is a neurodegenerative disorder that causes dementia among mainly elderly people and is increasing in prevalence in industrialized societies from 1 to 3 % in 60-65 year-olds to as much as 50 % by age 95. This disease is complex. Multiple genes are involved, and they potentially affect each other. LÄS MER

7. 5. On CNS injury and olfactory ensheathing cell engraftment strategies

   Författare :I-Hui Lee; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : The intrinsic regenerative capacity of the adult mammalian central nervous system (CNS) is limited because of lack of nerve-growth stimulatory factors and presence of an insurmountable molecular environment for injured axons. This thesis aims to study neural regeneration following adult CNS injury, using rodent models of spinal cord injury, dorsal root avulsion, and Parkinson s disease. LÄS MER