Sökning: "eye irritation"

Visar resultat 1 - 5 av 10 avhandlingar innehållade orden eye irritation.

  1. 1. Activation and Regulation of TRPV1 : Studies in Recombinant Human Neuroblastoma TRPV1-SHSY5Y Cells

    Författare :Johanna EL Andaloussi-Lilja; Anna Forsby; Antonio Ferrer-Montiel; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; nociception; neurotrophic factors; eye irritation; stable transfection; Ca2 ; Neurochemistry; Neurokemi; Neurochemistry and Molecular Neurobiology; neurokemi med molekylär neurobiologi;

    Sammanfattning : TRPV1 is a transmembrane non-selective cation channel with preference for Ca2+. The receptor is primarily localised on dorsal root ganglion neurons and is activated by numerous endogenous and exogenous potentially irritating ligands eliciting pain. LÄS MER

  2. 2. A study on the vascular effects of prostaglandin F2α[ and latanaprost in the eye with special reference to the surface hyperaemia after topical administration

    Författare :Maria Astin; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical biosciences; Prostaglandin F2a; Prostaglandin F2a-isopropyl ester; latanoprost; latanoprost acid; ocularhyperaemia; blood flow; sensory nerves; veins; arteries; nitric oxide; substance P; CGRP; Farmaceutisk biovetenskap; Biopharmacy; Biofarmaci; Pharmacognosy; farmakognosi;

    Sammanfattning : The ocular hypotensive effect of topically applied prostaglandins is usually accompanied byconjunctival hyperaemia and irritation. The purpose of the present study was to investigate thepharmacological mechanism of the ocular surface hyperaemia induced by topically appliedprostaglandins, particularly prostaglandin F2α (PGF2α) and its synthetic analogue latanoprost, aselective FP prostanoid receptor agonist. LÄS MER

  3. 3. Indoor environment and air quality in hospital units : Symptoms and signs

    Författare :Klas Nordström; Uppsala universitet; []
    Nyckelord :Medical sciences; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; arbets- och miljömedicin; Occupational and Environmental Medicine;

    Sammanfattning : Indoor environment may influence the occurrence of symptoms such as eye, skin and upper airway irritation, headache and fatigue. The aim of the dissertation was to study relations between subjective indoor air quality, such symptoms, clinical signs from the nose and the eyes and the physical indoor environment, in particular the effect of dampness, type of building, and air humidification. LÄS MER

  4. 4. Experimental studies on acute health effects of acrolein and other aldehydes

    Författare :Aishwarya Mishra Dwivedi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Aldehydes are reactive and ubiquitous in indoor as well as outdoors and can give rise to significant health problems in humans, e.g. irritation of the eyes and toxic effects on the upper respiratory tract. This thesis focuses on the irritating and inflammatory properties of three commonly occurring aldehydes; acrolein, crotonaldehyde and hexanal. LÄS MER

  5. 5. Dimethylethylamine and dimethylbenzylamine in foundries and the epoxy industry : Analysis, metabolism, biological monitoring, toxicological effects and occupational exposure

    Författare :Bengt Ståhlbom; Christer Edling; Östergötlands Läns Landsting; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Dimethylethylamine (DMEA) and dimethylbenzylamine (DMBA) are tertiary aliphatic amines, used as catalysts e.g., in mould core manufacturing and heat cured epoxy systems. Health effects such as visual disturbances and respiratory irritation occur among workers handling DMEA and airway symptoms are recorded by many workers exposed to DMBA. LÄS MER