Sökning: "neurotrophic factors"

Visar resultat 1 - 5 av 122 avhandlingar innehållade orden neurotrophic factors.

  1. 1. Neurotrophic factors and neuronal plasticity

    Författare :Sten Linnarsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The neurotrophic factors were originally discovered because of their ability to rescue neurons during a period of naturally occurring programmed cell death. This gave rise to the neurotrophic factor hypothesis which states that specific target-derived factors protect and support subpopulations of innervating neurons, thereby regulating the pattern and quantity of innervation properly for each target tissue. LÄS MER

  3. 2. Neurodegeneration in amyotrophic lateral sclerosis : neurotrophic factors and monoamine oxidase B

    Författare :Jonas Ekblom; Uppsala universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : .... LÄS MER

  4. 3. Pituitary adenylate cyclase activating polypeptide : Expression and neurotrophic activity in the rat brain

    Författare :Ylva Skoglösa; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; in situ hybridisation; rat; TBI; BDNF; NGF; GDNF; PACAP; PRI; TUNEL; apoptosis; CNS; PNS; neuropeptides; neurotrophic factors; reactive oxygen species; Neurovetenskap; Neurology; Neurologi; Neurology; neurologi;

    Sammanfattning : Neurotrophic factors play an important role in regulating naturally occurring cell death during neurogenesis. In addition to classical neurotrophic factors, some neurotransmitters and neuropeptides have been shown to exhibit neurotrophic activities. LÄS MER

  5. 4. Neurotrophic and immune regulatory factors in neuroinflammation

    Författare :Alexander W Gielen; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Neurotrophins; EAE; MS; TIM; Neuroprotection;

    Sammanfattning : Inflammatory reactions in the nervous system act as a double-edged sword. On the one hand, neuroinflammation can have very devastating effects on the nervous system, leading to neurological dysfunction. LÄS MER

  7. 5. Intrinsic and extrinsic factors controlling the differentiation of human midbrain progenitor cells

    Författare :Nicolaj Christophersen; Institutionen för experimentell medicinsk vetenskap; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicin människa och djur ; Medicine human and vertebrates ; neurotrophic factors; Parkinson s disease; microarray; dopaminergic; Embryonic stem cells; neural stem cells;

    Sammanfattning : Parkinson's disease (PD) is a common neurodegenerative disorder characterized by motor deficits. Levodopa treatment provides marked symptomatic relief. However, within 5-10 years after the start of Levodopa treatment, most PD patients display a gradual loss of drug efficacy. LÄS MER