Sökning: "expression quantitative trait loci"

Visar resultat 11 - 15 av 28 avhandlingar innehållade orden expression quantitative trait loci.

1. 11. Genomics of chicken domestication and feralisation

   Författare :Martin Johnsson; Dominic Wright; Per Jensen; Dirk-Jan de Koning; Linköpings universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

   Sammanfattning : Domestication can serve as a study system of rapid evolutionary change with wide-ranging effects on traits in animals. The chicken was domesticated from the Red Junglefowl and has diverged in behaviour, morphology and life history traits. LÄS MER

3. 12. Genetic and immunological regulation of neuroinflammation

   Författare :Mélanie Thessén Hedreul; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Multiple Sclerosis (MS) affects young adults and is characterized by chronic inflammation and demyelination in the central nervous system that leads to progressive worsening of disease. The cause of MS is incompletely understood and there is a need for more specific and effective treatments. LÄS MER

4. 13. Exploring the transcriptome of the brain

   Författare :Allissa Dillman; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Our knowledge of the transcriptome has become much more complex since the days of the central dogma of molecular biology. We now know that splicing takes place to create potentially thousands of isoforms from a single gene, and we know that RNA does not always faithfully recapitulate DNA if RNA editing occurs. LÄS MER

5. 14. Evolution of Flowering Time in the Tetraploid Capsella bursa-pastoris (Brassicaceae)

   Författare :Tanja Slotte; Martin Lascoux; Ulf Lagercrantz; Juliette de Meaux; Uppsala universitet; []
   Nyckelord :Biology; flowering time; homoeolog; hybridization; introgression; microarray; multiple origins; polyploid; QTL; Biologi;

   Sammanfattning : Although polyploidy is believed to be a major source of evolutionary novelty, few studies have examined the genetic basis of phenotypic variation in wild polyploids. In this thesis I have studied the genetic basis of flowering time variation in the wild tetraploid crucifer Capsella bursa-pastoris, as well as the evolutionary history of this species. LÄS MER

7. 15. FAM167A-BLK is a susceptibility locus in autoimmune diseases : characterization of the FAM167 gene family

   Författare :Lara Mentlein; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Autoimmune diseases are complex multifactorial diseases, and their pathogenesis is only partially understood, but both genetic, as well as environmental factors, have been correlated to an increased risk for the diseases. Genome-wide association studies of Sjögren’s syndrome, systemic lupus erythematosus, and rheumatoid arthritis have identified many risk loci; most studies include associations to the FAM167A-BLK locus. LÄS MER