Sökning: "diseases"

Visar resultat 26 - 30 av 4240 avhandlingar innehållade ordet diseases.

  1. 26. Systemic fungal diseases in natural plant populations

    Författare :Anders Wennström; Lars Ericson; Peter G. Ayres; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Systemic diseases; rust; smut; Puccinia minussensis; Lactuca sibirica; Puccinia pulsatillae; Pulsatilla pratensis; lateral growth; abiotic factors; disease transmission; Svampsjukdomar hos växter;

    Sammanfattning : The purpose of this thesis was to study interactions between systemic fungal diseases and perennial plants. Using the systemic rust Puccinia minussensis on the host plant Lactuca sibirica, and the rust Puccinia pulsatillae on the host plant Pulsatilla pratensis, this thesis focused on: (i) the effects of systemic diseases on their hosts (ii) host and pathogen responses to abiotic factors, (iii) the importance of life history strategies for understanding host-pathogen interactions, and (iv) the evolutionary consequences of living in close associations. LÄS MER

  3. 27. Patterns in big data bioinformatics : Understanding complex diseases with interpretable machine learning

    Författare :Mateusz Garbulowski; Jan Komorowski; Ryan J. Urbanowicz; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; complex diseases; big data; machine learning; transcriptomics; life sciences; rough sets; Bioinformatics; Bioinformatik;

    Sammanfattning : Alterations in the flow of genetic information may lead to complex diseases. Such changes are measured with various omics techniques that usually produce the so-called “big data”. Using interpretable machine learning (ML), we retrieved patterns from transcriptomics data sets. LÄS MER

  4. 28. Autosomal Dominant Leukodystrophy with Autonomic Symptoms and Rippling Muscle Disease : Translational Studies of Two Neurogenetic Diseases

    Författare :Jimmy Sundblom; Anja Smits; Raili Raininko; Niklas Dahl; Klas Kullander; Åsa Fex-Svenningsen; Marianne de Visser; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Inborn genetic diseases; Leukoencephalopathies; Lamin type B; Muscular disease; Caveolin 3; Neurology; Neurologi;

    Sammanfattning : There is a large variety of diseases caused by single-gene mutations. Although most of these conditions are rare, together they impose a significant burden to the population. LÄS MER

  5. 29. Uncovering biomarkers and molecular heterogeneity of complex diseases : Utilizing the power of Data Science

    Författare :Sara Younes; Linda Holmfeldt; Jan Komoroski; Aedin Culhane; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Complex Disease; Cancer; Autoimmune diseases; Acute Myeloid Leukemia; Systemic Lupus Erythematosus; Bioinformatics; Machine Learning; Data Science; Statistical Analysis; Bioinformatics; Bioinformatik; Computer Science; Datavetenskap;

    Sammanfattning : Uncovering causal drivers of complex diseases is yet a difficult challenge. Unlike single-gene disorders complex diseases are heterogeneous and are caused by a combination of genetic, environmental, and lifestyle factors which complicates the identification of patient subgroups and the disease causal drivers. LÄS MER

  7. 30. Self-reported atopic diseases, atopy patch test reactions, and contact allergy in adolescents

    Författare :Ada Uldahl; Yrkes- och miljödermatologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; atopic dermatitis; Adolescents; atopy patch test; Atopic: epidemiology; patch testing; allergic contact dermatitis; repeated open application test;

    Sammanfattning : .... LÄS MER