Sökning: "cell adhesion molecules"

Visar resultat 1 - 5 av 191 avhandlingar innehållade orden cell adhesion molecules.

  1. 1. The role of cell adhesion molecules in tissue formation and organogenesis

    Författare :Farzad Esni; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; cell adhesion cadherins N-CAM pancreas development mouse organogenesis;

    Sammanfattning : Cell adhesion molecules (CAMs) are cell surface glycoproteins that promote connection between two adjacent cells or between a cell and extra cellular matrix. These interactions are essential for tissue organisation during development and for the maintenance of tissue integrity in adult organisms. LÄS MER

  3. 2. Integrin Signaling in Cell Adhesion and Mechanotransduction : Regulation of PI3K, AKT, and ROS

    Författare :Kathrin Stephanie Zeller; Staffan Johansson; Kristofer Rubin; John Couchman; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; integrin; ROS; PI3K; AKT; mechanosignaling; actin polymerization; spreading;

    Sammanfattning : Integrins are a family of conserved cell surface receptors found throughout the animal kingdom. They comprise 24 dimers in mammals, and regulate a number of processes including cell survival, differentiation, and migration. LÄS MER

  4. 3. Thrombospondin 1, an autocrine regulator in T cell adhesion and migration

    Författare :ShuShun Li; Karl-Gösta Sundqvist; Jan Holgersson; Claes Dahlgren; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; T cell; adhesion; migration; thrombospondin; Immunologi; Immunology; Immunologi; immunologi; Immunology;

    Sammanfattning : Lymphocytes, the principal cells of the immune system, perform the immune function throughout the body by their unique capacity to circulate in blood stream and lymphatic vessels and migrate in lymphoid and non-lymphoid tissues. The mechanisms regulating lymphocyte adhesion and migration, interactions with cells and components within the extracellular matrix are not fully understood. LÄS MER

  5. 4. Cell Contacts and Airway Epithelial Damage in Asthma

    Författare :Shahida Shahana; Godfried Roomans; Rolf Odselius; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Anatomy; Desmosomes; tight junctions; major basic protein; eosinophil; cytokines; epithelial damage.; Anatomi; Anatomy; Anatomi;

    Sammanfattning : Airway epithelial damage is commonly found in asthma patients. Epithelial damage was investigated with special reference to contacts between epithelial cells.Eosinophils, common in allergic asthma, secrete cationic proteins, particularly major basic protein (MBP). LÄS MER

  7. 5. Syndecan - Regulation and Function of its Glycosaminoglycan Chains

    Författare :Anna S. Eriksson; Dorothe Spillmann; Catherine Merry; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; heparan sulfate; chondroitin sulfate; integrin; cell motility; fibroblast growth factor signaling; pharyngeal cartilage; biosynthesis regulation; Medical Science; Medicinsk vetenskap;

    Sammanfattning : The cell surface is an active area where extracellular molecules meet their receptors and affect the cellular fate by inducing for example cell proliferation and adhesion. Syndecans and integrins are two transmembrane molecules that have been suggested to fine-tune these activities, possibly in cooperation. Syndecans are proteoglycans, i.e. LÄS MER