Sökning: "brigatinib"
Hittade 2 avhandlingar innehållade ordet brigatinib.
1. Anaplastic lymphoma kinase activity, a therapeutic target, suppresses neuroblastoma cell differentiation
Sammanfattning : Neuroblastoma (NB) is the most common extracranial pediatric solid malignancy caused by the failed differentiation of precursor cells of the developing sympathetic nervous system. NB accounts for about 15% of childhood cancer-related deaths. LÄS MER
2. Genetic determinants of lung cancer and their application toward therapeutics. The role of ZFP148 transcription factor and anaplastic lymphoma kinase (ALK) fusion proteins in non-small cell lung cancer
Sammanfattning : Lung cancer causes severe morbidity and mortality in millions of patients globally each year. Anaplastic lymphoma kinase (ALK) mutations facilitate neoplastic growth of lung cancer in adults and neuroblastoma in pediatric patients. LÄS MER
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