Sökning: "astroglial cell"

Visar resultat 1 - 5 av 33 avhandlingar innehållade orden astroglial cell.

  1. 1. Astroglial Cells : Role in Neurodegenerative-Inflammatory Processes in the Central Nervous System

    Författare :Gun Eriksson; Karl Åkerman; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Chemistry; Kemi; neurokemi och neurotoxikologi; Neurochemistry and Neurotoxicology;

    Sammanfattning : Inflammatory processes, mediated by the pro-inflammatory cytokines interleukin (IL) -1a/b, tumor necrosis factora(TNFa), IL-6 and excitotoxic actions of glutamate, are proposed to be implicated in neurodegenerative diseases, such as Alzheimer's disease.A neurotoxic fragment ofb-amyloid,bA25-35, was shown to induce a reactive phenotype of primary astrocytes and microglial cells in a time-dependent manner. LÄS MER

  2. 2. Glutathione in the brain. Studies on efflux and possible implications in neurotoxicity

    Författare :Camilla Wallin; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glutathione; excitotoxicity; hypoxia-ischemia; brain; rat; anoxia-aglycemia; g-glutamyl transpeptidase; glutamate; NMDA; oxidative stress; mitochondria; amino acids;

    Sammanfattning : Neuronal cell death in acute insults such as stroke, trauma and epilepsy involves overactivation of glutamate receptors, calcium influx and increased formation of potentially toxic reactive oxygen species. Glutathione is a key component in the antioxidant defense system against reactive oxygen species. LÄS MER

  3. 3. Inflammatory Signaling Across the Blood-Brain Barrier and the Generation of Fever

    Författare :Anna Eskilsson; David Engblom; Annika Thorsell; Göran Engberg; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Fever is a cardinal sign of inflammation and is evolutionary conserved. Fever is known to be beneficial during acute inflammation, but over time and if very high it can be detrimental. LÄS MER

  4. 4. Connexin43 in astroglial gap junctions. Regulation by age, neurotransmitters, GH and IGF-I

    Författare :N David Åberg; Göteborgs universitet; []
    Nyckelord :Connexin43; rat; development; hypophysectomy; primary culture; ; mRNA; gap junction; somatotropin; IGF-I; serotonin; glutamate; ; brain region heterogeneity; calcium wave; astrocyte; astroglial cell; ; gap junctional coupling.;

    Sammanfattning : Connexins form gap junctions that are aqueous pores allowing low-molecular (.... LÄS MER

  5. 5. Dynamic fluorescence imaging with applications to astroglial cells

    Författare :Siamak Khatibi; Chalmers tekniska högskola; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; calcium wave; image analysis; volume estimation. astrocyte; intercellular signaling; imaging; 3D reconstruction; cell volume;

    Sammanfattning : .... LÄS MER