Sökning: "analogues"
Visar resultat 6 - 10 av 417 avhandlingar innehållade ordet analogues.
6. GALIELLALACTONE ANALOGUES – SYNTHESIS AND PROPERTIES
Sammanfattning : Cancer cells use normal cell signalling pathways in a proliferative fashion in order to prolong their own survival. Inhibition of one of the major signal proteins, STAT3 (Signal Transducer and Activator of Transcription 3) has previously been shown to induce apoptosis. LÄS MER
7. Synthesis of some vasopressin analogues : evaluation of their agonistic and antagonistic properties especially in the antidiuretic assay
Sammanfattning : .... LÄS MER
8. Synthesis and applications of analogues of Tröger's base as molecular tubes, receptor and ligands
Sammanfattning : Tröger’s base was synthesized for the first time in 1887. The molecule is rigid, C2-symmetric and has a 90° angle, forming a chiral hydrophobic pocket. In this thesis, the synthesis of new analogues of Tröger’s base is described. 2- and 3-halo-substituted anilines have for the first time been condensed to Tröger’s base analogues. LÄS MER
9. Polyamine analogues inhibit neuroblastoma cell growth
Sammanfattning : Abstract Neuroblastoma is a highly malignant neoplasm found in children. Although children with high-risk neuroblastoma respond to chemotherapy, relapses are common and an estimated long-time survival prognosis is approximately 15%. Thus, there is a tremendous need for new chemotherapeutic drugs for the treatment for neuroblastoma. LÄS MER
10. Dissolution of fluorite type surfaces as analogues of spent nuclear fuel : Production of suitable analogues and study the effect of surface orientation on dissolution
Sammanfattning : It is accepted worldwide that the best final solution for spent nuclear fuel is to bury it in deep geological repositories. Despite the physical and chemical barriers that are supposed to isolate the nuclear waste for at least 100.000 years, some uncertainty factors may cause underground water to get in contact with the nuclear waste. LÄS MER