Sökning: "VGLUT2"

Visar resultat 11 - 13 av 13 avhandlingar innehållade ordet VGLUT2.

  1. 11. Neuromodulation shapes interneuron communication in the mouse striatum

    Författare :Matthijs Constantijn Dorst; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : A proper understanding of cognition relies on detailed knowledge about the functional connectivity within and between brain areas. The striatum is generally regarded as the input structure to the basal ganglia, a group of subcortical nuclei that have been demonstrated to be involved in motor function and reward, amongst other functions. LÄS MER

  3. 12. Calcium-binding proteins as markers and functional determinants of neurons in pain networks

    Författare :Mingdong Zhang; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The thesis focuses on the anatomical and cellular distribution of three EF-hand calcium binding proteins, secretagogin, neuronal calcium-binding protein 1 (NECAB1) and NECAB2 in dorsal root ganglia (DRGs) and spinal cord of three species, mouse, rat and human, and their possible roles in pathophysiological pain. In Paper I and Paper IV, we report that the expression of secretagogin is limited to a small subpopulation of peptidergic neurons in mouse and human DRGs expressing calcitonin generelated peptide (CGRP). LÄS MER

  4. 13. Brain control of energy balance : localization and regulation of proteins involved in the central control of food intake and body weight

    Författare :Maria Collin; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :AGRP; arcuate nucleus; brainstem; CART; GABA; Glutamate; GPCR; habenular complex; immunohistochemistry; in situ hybridization; hypothalamus; leptin; leptin receptor; LHA; MCH; NPY; Ob-Rb; POMC; serotonin; STAT3; transporter; ventromedial hypothalamic nucleus; VGLUT1-3.;

    Sammanfattning : Obesity has become a worldwide threat to human well-being and is now so common that it is beginning to replace undernutrition and infectious disease as the most significant contributor to ill health. Obesity increases the risk for aquiring serious diseases such as diabetes type 2, hypertension, coronary heart disease and certain forms of cancer. LÄS MER