Sökning: "Tumor-associated macrophages"
Visar resultat 1 - 5 av 28 avhandlingar innehållade orden Tumor-associated macrophages.
1. Targeting the prostate tumor microenvironment and vasculature : the role of castration, tumor-associated macrophages and pigment epithelium-derived factor
Sammanfattning : BACKGROUND: Prostate cancer is the most common cancer among Swedish men. For patients with metastatic prostate cancer the standard therapy is castration, a treatment that initially provides symptomatic relief but unfortunately is not curative. New therapeutic targets for advanced prostate cancer are therefore needed. LÄS MER
2. Exploring mechanisms regulating the heterogeneity of tumor-associated macrophages
Sammanfattning : Accumulation of macrophages in the tumor microenvironment is associated to poor prognoses in most human cancers. Tumor-associated macrophages (TAMs) represent a heterogeneous and plastic population of cells that contribute to tumor growth, metastatic dissemination, angiogenesis, and immune suppression. LÄS MER
3. The impact of Wnt5a signaling and tumor associated macrophages in breast cancer
Sammanfattning : Breast cancer is the most common cancer among women worldwide with approximately 1.150.000 new cases each year and accounting for over 400.000 deaths per year. LÄS MER
4. Tumor-associated macrophages and microglia : double-edged sword in tumor evolvement and invasion
Sammanfattning : Tumor-associated macrophages (TAMs) are among the most abundant cell types in the tumor microenvironment. TAM infiltration is usually linked to tumor progression, metastasis and poor clinical outcome in most human cancers. LÄS MER
5. Function of Innate Immune Cells in Breast Cancer
Sammanfattning : Tumor associated macrophages (TAMs) are key cells in creating an immunosuppressive tumor microenvironment (TME). In general, presence of TAMs is associated with worse outcome in cancer patients. Macrophages with anti-tumor effect can be found in the TME but are usually in minority. LÄS MER