Sökning: "TaN"

Visar resultat 1 - 5 av 89 avhandlingar innehållade ordet TaN.

  1. 1. ADP regulation of insulin secretion and beta-cell apoptosis

    Författare :Chanyuan Tan; Kardiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; P2Y; β-cell; ADP; insulin; apoptosis; autocrine; ectonucleotidase;

    Sammanfattning : The aims of this dissertation were to investigate the effects of extracellular purines on insulin secretion, and apoptosis in mouse pancreatic islets and β-cells; to examine if high glucose and free fatty acids induces β-cell apoptosis via autocrine effects of ADP acting on the P2Y13 receptor; and to investigate the modulation of extracellular purines in vascular smooth muscle cells (VSMCs) through ectonucleotidase or ATP release under the effect of high glucose. The expression of the ADP receptors P2Y1 and P2Y13 were shown in both mouse pancreatic islets and isolated β-cells using real-time PCR quantification. LÄS MER

  3. 2. High-Speed Analog-to-Digital Converters in CMOS

    Författare :Siyu Tan; Integrerade elektroniksystem; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; A D converters; CMOS circuit design; ΔΣ ADC; high-speed ADC; Nyquist-rate ADC; oversampled ADC; SAR ADC; 5G;

    Sammanfattning : The Analog to Digital (A/D) Converters (ADC) are vital components in high-performance radio devices. In the receiver end, the signal received by the analog front-end can not be directly analyzed by the digital core, thus requiring high-performance ADC circuits acting as bridges connecting the analog and digital domain. LÄS MER

  4. 3. Platelet-regulated CD4+ T effector cell responses in atherosclerosis

    Författare :Shuai Tan; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Atherosclerosis (AS) is a thrombotic and inflammatory disease of the medium- and largesized arteries. Platelets participate in all stages of its formation, forming thrombus at the ruptured plaque; meanwhile, CD4+ T cells are a key driving force of inflammation, plaque formation and instability. LÄS MER

  5. 4. Posttranscriptional regulation of gene expression in retroviruses and human papillomaviruses

    Författare :Wei Tan; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :CTE; EIAV; HIV- 1; HPV; Rev; RRE; splice site; SRV- 1; 3 UTR Stockholm 1996 Doctoral Thesis;

    Sammanfattning : Human immunodeficiency virus type I (HIV-1) is the prototype of complex retroviruses, whereas human papillomaviruses (HPVs) are nonenveloped, cricular double-stranded DNA viruses. The HIV-1 Rev protein is a posttranscriptional regulator, which acts on its target RNA sequence termed the Rev-responsive element (RRE) to facilitate nuclear export of unspliced and partially spliced HIV-1 mRNAs, and to improve their stability and translatability. LÄS MER

  7. 5. Correctness and Safety in Planning and Control via State-Space Partitions and Barrier Functions

    Författare :Xiao Tan; Dimos V. Dimarogonas; Samuel Coogan; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Dynamical systems; Control barrier functions; Optimeringslära och systemteori; Optimization and Systems Theory;

    Sammanfattning : Autonomous systems have become increasingly prevalent in various industries, ranging from household cleaning robots to line inspection drones and copilot vehicles. Ensuring real-time safety is becoming a critical issue when the environment is rapidly changing. LÄS MER