Sökning: "Sven Hammarström"
Hittade 2 avhandlingar innehållade orden Sven Hammarström.
1. The enzymatic machinery of leukotriene biosynthesis : Studies on ontogenic expression, interactions and function
Sammanfattning : Leukotrienes (LTs) are biologically active arachidonic acid (AA) derivatives generated by the 5-lipoxygenase (5-LO) pathway. They are produced by myeloid cells. 5-LO converts AA to LTA4 in cooperation with 5-LO activating protein (FLAP). LTA4 is converted to LTB4, by LTA4-hydrolase (LTA4H) or to LTC4 by LTC4-synthase (LTC4S). LÄS MER
2. Leukotriene C4 synthase : studies on oligomerization and subcellular localization
Sammanfattning : Leukotrienes (LTs) are polyunsaturated fatty acid derivatives formed by oxygenation of arachidonic acid via the 5-lipoxygenase (5-LO) pathway. Upon activation of inflammatory cells 5-LO is translocated to the nuclear envelope where it converts arachidonic acid to the unstable epoxide LTA4. LÄS MER