Sökning: "Suramin"

Visar resultat 6 - 9 av 9 avhandlingar innehållade ordet Suramin.

1. 6. The glycobiology of human adenovirus infections : implications for tropism and treatment

   Författare :Naresh Chandra; Niklas Arnberg; Lars Frängsmyr; Gunnel Haldén; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; denovirus; cellular receptor; glycosaminoglycan; sialic acid; decoy receptors; tropism; epidemic keratoconjunctivitis; antiviral drugs; GAG-mimetic; obesity; medicinsk virologi; Medical Virology;

   Sammanfattning : Human adenoviruses (HAdVs) are common human pathogens, causing gastrointestinal, ocular, and respiratory infections on a regular basis. Epidemic keratoconjunctivitis (EKC) is a severe ocular infection for which no approved antivirals are available. LÄS MER

3. 7. Experimental inhibition of proliferative retinopathy

   Författare :Sylvia Almlöf Sarman; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Retinal ischemic diseases like retinopathy of prematurity (ROP), diabetic retinopathy (DRP) and retinal vein occlusion, with preretinal neovascularization (angiogenesis) that may lead to vitreous hemorrhages and retinal detachment with subsequent vision loss and blindness is a global health problem. By analyzing the potential role of molecules acting at different levels of the angiogenic cascade the presented studies aimed to widen our understanding of retinal ischemic diseases on a molecular, cellular and morphologic level. LÄS MER

4. 8. Anthracycline pharmacodynamics and pharmacokinetics in acute myeloid leukemia

   Författare :Alex Bogason; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : The goal of this thesis has been to study pharmacodynamics and pharmacokinetics of anthracyclines in acute myeloid leukemia (AML) with the ultimate goal to improve chemotherapy: 1. By studying the relation between daunorubicin (DNR) and idarubicin (IDA) uptake in vitro and in vivo and apoptosis in vitro in leukemic cells isolated from patients with AML. LÄS MER

5. 9. Pharmacological studies on uptake, metabolism, and resistance to anti-cancer drugs : insights into the treatment of leukemia

   Författare :Hazhar Karim; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Leukemia is blood cancer that begins in the bone marrow and characterized by abnormal production of white blood cells. Due to advances in treatment, there has been a dramatic increase in survival rate for patients with different types of leukemia. LÄS MER