Sökning: "SNI"
Hittade 5 avhandlingar innehållade ordet SNI.
1. "Det handlar om vår framtid" : Hur elevers scientific literacy kan utvecklas genom SNI-argumentation i kemiundervisning
Sammanfattning : En individ i dagens samhälle kommer ständigt i kontakt med olika frågor som är kopplade till naturvetenskap. Val ska göras, beslut ska fattas. LÄS MER
2. Att ta ställning : Gymnasieelevers argumentation och beslutsfattande om sociovetenskapliga dilemman
Sammanfattning : This thesis aims to explore students’ argumentation and decision-making relating to authentic socioscientific issues (SSI). The ability to make informed decisions about socio scientific issues has been recognized to be an important element in science education to achieve the goal of scientific literacy. LÄS MER
3. Vasomotor symptoms in postmenopausal women : the role of acupuncture and calcitonin gene-related peptide
Sammanfattning : A majority of postmenopausal women experience vasomotor symptoms, which have a significant impact on the women's quality of life. Estrogens are the treatment of choice but can for different reasons not be used by all women. There is therefore a great need for viable alternative treatments. LÄS MER
4. Development of Substance P 1–7 Related Peptides and Peptidomimetics : Targeting Neuropathic Pain
Sammanfattning : The neuropeptide substance P 1–7 (SP1–7, H-Arg1-Pro2-Lys3-Pro4-Gln5-Gln6-Phe7-OH) and its amidated analogue SP1–7 amide, have displayed intriguing effects in experimental models for neuropathic pain acting on a specific, yet unknown SP1–7 target. The aim of this thesis was to design and synthesise SP1–7 related peptides and peptidomimetics, to be used as research tools to study the SP1–7 system, and to serve as drug leads in the neuropathic pain area. LÄS MER
5. Leukotriene A4 hydrolase : exploration of the active sites and catalytic mechanisms by site-directed mutagenesis
Sammanfattning : Leukotriene (LT) A4 is a pivotal intermediate in the biosynthesis of leukotrienes, a family of potent lipid mediators involved in a variety of inflammatory and allergic disorders. The bifunctional zinc metalloenzyme LTA4 hydrolase converts LTA4 into LTB4, one of the most potent chemotaxins known to date. LÄS MER