Sökning: "Rph1"
Hittade 4 avhandlingar innehållade ordet Rph1.
1. Studies of Budding Yeast Transcription Factors Acting Downstream of Nutrient Signaling Pathways
Sammanfattning : Being able to respond to extracellular cues such as nutrients and growth factors is of vital importance to all living cells. Pathways have therefore evolved which can sense the extracellular status, transmit a signal through the cell and affect gene expression, which ultimately enables adaptation. LÄS MER
2. Genome-wide Studies of Transcriptional Regulation in Yeast
Sammanfattning : In this thesis, nutrient signalling in yeast is used as a model to study several features of gene regulation, such as combinatorial gene regulation, the role of motif context and chromatin modifications. The nutrient signalling system in yeast consists of several pathways that transmit signals about the availability of key nutrients, and regulate the transcription of a large part of the genome. LÄS MER
3. Short and long-term regulation of autophagy
Sammanfattning : Autophagy is a conserved catabolic pathway triggered by stress conditions in which portions of the cytoplasm, damage organelles, misfolded proteins and intracellular bacteria are delivered and degraded in the lysosome/vacuoles. Thus, an efficient induction and completion of the process is required to ensure a proper homeostasis of the cell. LÄS MER
4. The return of the nucleus : epigenetic regulation of autophagy
Sammanfattning : Autophagy is an evolutionary conserved catabolic process activated in response to a variety of cellular stresses, for example nutrient deprivation or chemotherapy. During autophagy, cells engulf parts of their cytplasm in a double-membrane vesicle, where misfolded proteins or damaged organelles are degraded. LÄS MER