Sökning: "Roza Ghotbi"

Hittade 1 avhandling innehållade orden Roza Ghotbi.

  1. 1. Genetic, epigenetic and environmental factors of importance for CYP1A2 catalyzed drug metabolism

    Författare :Roza Ghotbi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The heme containing cytochrome P450 (CYP450) enzymes participate in the phase I metabolism of drugs and other xenobiotics as well as endogenous substrates. CYP1A2 is one of the major CYP450 enzymes and account for about 13% of the total CYP450 content in the liver and is responsible for the metabolism of several clinically used drugs, e. LÄS MER