Sökning: "Peter Sartipy"
Hittade 4 avhandlingar innehållade orden Peter Sartipy.
1. Proteoglycans, group IIA phospholipase A2, and lipoproteins.Potential involvement in atherogenesis
Sammanfattning : Atherosclerosis is a multifactorial complex disease characterized by a focal accumulation of ApoB-100 containing lipoproteins, extracellular matrix (ECM), and cells in the arterial intima accompanied by an inflammatory reaction. In vivo and in vitro data supports the hypothesis that sulfated extracellular proteoglycans may be responsible for the selective retention of low density lipoproteins (LDL) in the arterial wall. LÄS MER
2. Organs-on-chips for the pharmaceutical development process : design perspectives and implementations
Sammanfattning : Organs-on-chips are dynamic cell culture devices created with the intention to mimic organ function in vitro. Their purpose is to assess the toxicity and efficacy of drugs and, as early as possible in the pharmaceutical development process, predict the outcome of clinical trials. LÄS MER
3. In vitro toxicity testing using human pluripotent stem cell derivatives
Sammanfattning : .... LÄS MER
4. Transcriptional profiling of human embryonic stem cells and their functional derivatives
Sammanfattning : Human embryonic stem cells (hESCs) represent populations of pluripotent, undifferentiated cells with unlimited replication capacity, and with the ability to differentiate into any functional cell type in the human body. Based on these properties, hESCs and their derivatives provide unique model systems for basic research on embryonic development. LÄS MER