Sökning: "PKD"

Hittade 2 avhandlingar innehållade ordet PKD.

1. 1. Novel roles of ErbB3 receptor tyrosine kinase in vesicular trafficking

   Författare :Ana Rosa Saez-Ibañez; Ingvar Ferby; Carl-Henrik Heldin; Johanna Ivaska; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ErbB3; Integrin; GGA3; Rabaptin5; PKD; Ack1; endocytic recycling; exosome; Biology with specialization in Molecular Cell Biology; Biologi med inriktning mot molekylär cellbiologi;

   Sammanfattning : ErbB3 is a catalytically impaired receptor tyrosine kinase (RTK) from the EGFR family. Upon ligand binding, ErbB3 forms heterodimers with other members of the family and triggers phosphorylation cascades that promote crucial cellular functions as proliferation, differentiation and survival. LÄS MER

3. 2. The Molecular Mechanism of Aggression and Feeding Behaviour in Drosophila melanogaster

   Författare :Philip Goergen; Helgi Schiöth; Michael Williams; Simon Tuck; Uppsala universitet; []
   Nyckelord :Drosophila; aggression; obesity; homeostasis;

   Sammanfattning : Obesity is a complex disorder which has become a growing health concern. Twin studies have demonstrated a strong genetic component to the development of obesity and genome wide association studies have identified several genetic loci associated with it. However, most of these loci are still poorly understood in a functional context. LÄS MER