Sökning: "P-selectin expression"
Visar resultat 1 - 5 av 29 avhandlingar innehållade orden P-selectin expression.
1. Platelet adhesion and P-selectin surface expression
Sammanfattning : Upon injury in a blood vessel, platelets become activated and adbere to prevent blood loss. Activated platelets express adhesion molecules on their surface that also make leukocytes adhere to the injury. One such molecule, which also is expressed on endothelium, is the glycoprotein P-selectin. LÄS MER
2. On the role of mast cells in chemokine-induced leukocyte recruitment
Sammanfattning : Leukocyte recruitment is considered to playa key role in numerous inflammatory diseases. Tissue accumulation of Jeukocytes is a multi-steps process comprising rolling, adhesion and transmigration. LÄS MER
3. Inflammatory mechanisms in experimental CNS trauma
Sammanfattning : Traumatic brain and spinal cord injuries are important causes of premature death and permanentdisability. To improve the treatment of CNS-injured patients increased knowledge about thepathophysiological events that mediate death or dysfunction of nervous tissue is urgently needed. LÄS MER
4. Mediator synergism in mast celldependent inflammation : role of histamine for leukocyte recruitment
Sammanfattning : The aim of the present thesis was to study functional interactions between histamine and chemotactic mediators, and the role of histamine for leukocyte recruitment in mast cell-dependent inflammation. Leukocyte rolling, adhesion and emigration. LÄS MER
5. Platelet function in diabetes mellitus : relationships to hyperglycaemia, antidiabetic treatment and microangiopathy
Sammanfattning : Diabetes mellitus is associated with accelerated atherosclerosis and increased morbidity and mortality in micro-and macrovascular complications. The metabolic derangements that accompany diabetes can adversely influence platelets and vascular endothelial function, which may contribute to the pathogenesis of diabetic angiopathy. LÄS MER