Sökning: "Oral tolerance"

Visar resultat 6 - 10 av 130 avhandlingar innehållade orden Oral tolerance.

  1. 6. Recurrent Aphthous Stomatitis - A study, with emphasis on host genetics, oral microbiota composition, and immunoregulatory networks

    Författare :Maria Bankvall; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Aphthous stomatitis; Oral mucosa; Oral medicine; Genome-wide association study; Genetic linkage; Association; Genetic polymorphism; Microbiota; Restriction fragment length polymorphism; Antigen-presenting cell; T-lymphocyte; Lymph node; Flow cytometry;

    Sammanfattning : Recurrent aphthous stomatitis (RAS) is one of the most common oral mucosal lesions. The aetiology is unknown and currently there is no consensus regarding suitable treatment regimens. LÄS MER

  3. 7. The role of exosomes and microflora in establishing mucosal tolerance and the protection against allergic disease

    Författare :Nina Almqvist; Göteborgs universitet; []
    Nyckelord :oral tolerance; exosomes; allergy;

    Sammanfattning : The role of exosomes and microflora in establishing mucosal tolerance and the protection against allergic disease Nina Almqvist, Departement of Rheumatology and Inflammation Research, The Sahlgrenska Academy University of Gothenburg, Guldhedsgatan 10A, 413 46 Göteborg, Sweden The breakdown of immune regulation to innocuous environmental antigens at mucosal sites can result in a number of different diseases such as, allergies and inflammatory bowel disease (IBD). Allergy is one of the most common diseases with a prevalence of up to 40% in children from developed countries. LÄS MER

  4. 8. Modulation of immune responses in murine collagen induced arthritis

    Författare :Fredrik Bäckström; Göteborgs universitet; []
    Nyckelord :Experimental arthritis; type II collagen; immunomodulation; oral tolerance;

    Sammanfattning : Murine collagen-induced arthritis (CIA) is the most common model for studying human rheumatoid arthritis (RA). Autologous or heterologous type II collagen (CII) emulsified in Freund´s complete adjuvant induces arthritis in susceptible mice, which is histopathologically similar to RA. LÄS MER

  5. 9. Impaired Glucose Tolerance in Childhood Obesity : Contribution of Glucagon, GLP-1 and Inflammation

    Författare :Hannes Manell; Peter Bergsten; Anders Forslund; Jens Juul Holst; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Childhood obesity; impaired glucose tolerance; type 2 diabetes; glucagon; glucagon-like peptide-1; dipeptidyl peptidase-4; inflammation; free fatty acids; insulin; visceral adiposity; Medicinsk vetenskap; Medical Science;

    Sammanfattning : In the wake of increased obesity prevalence, impaired glucose tolerance (IGT) and type 2 diabetes (T2D) in childhood and adolescence is increasingly common. Given the negative impacts these conditions have on health over time, understanding the pathophysiology in those affected early in life is important. LÄS MER

  7. 10. Oral tolerance mechanisms and the role of the microbiota

    Författare :Sofia M Östman; Göteborgs universitet; []
    Nyckelord :;

    Sammanfattning : The hygiene hypothesis state that microbial stimulation is necessary to fully activate and mature the immune system and to sustain tolerance mechanisms. Oral tolerance maintains immune homeostasis in the gut and prevents adverse reactions towards the comensal flora and Ags from the food and thus protects from development of allergies and inflammatory bowel diseases (IBD). LÄS MER