Sökning: "oral tolerance"

Visar resultat 1 - 5 av 130 avhandlingar innehållade orden oral tolerance.

  1. 1. The immunomodulatory function of staphylococcal superantigen on oral tolerance

    Författare :Anna Stern; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; oral tolerance; superantigen; hygiene hypothesis; staphylococcal enterotoxin;

    Sammanfattning : Exposure to soluble proteins via the gut gives rise to systemic tolerance, a phenomenon called oral tolerance. Failure of oral tolerance results in allergy, a disease that has increased during the last decades in Western industrialized countries. The cause of this rapid increase is unknown. LÄS MER

  3. 2. On the regulation of immune responses to dietary and self antigens

    Författare :Susanne Lindgren; Göteborgs universitet; []
    Nyckelord :Tolerance; regulatory T cells; self antigens; oral tolerance; dietary antigens; intestinal epithelial cells; exosomes; Staphylococcus aureus enterotoxin A;

    Sammanfattning : Regulatory mechanisms are necessary to avoid the misdirected aggressive immune responses responsible for the pathology seen in autoimmunity and allergy. Thymic-derived CD4+CD25+ regulatory T cells are indispensible for this regulation. We investigated if CD4+CD25+ Treg prevents auto-reactive responses in adult peripheral blood and cord blood. LÄS MER

  4. 3. Nickel allergy in a Swedish adolescent population and its relation to orthodontic treatment and lifestyle factors

    Författare :Ronny Fors; Berndt Stenberg; Maurits Persson; Arne Hensten; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adolescent; dental plaque; lifestyle; nickel; oral; orthodontic treatment; patch test; questionnaire; sensitisation; tolerance; Orthodontics; Ortodonti;

    Sammanfattning : Nickel stands out as the main cause of contact allergy in both children and adults, which has given rise to concern and the introduction of regulations by official bodies. Today´s youths are frequently exposed to body piercing and orthodontic treatment. LÄS MER

  5. 4. Immunological tolerance to antigens in the intestine

    Författare :Malin Karlsson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Rat; oral tolerance; serum factor; normal gut flora; exosomes;

    Sammanfattning : The major part of the immune system is found in the epithelium and lamina propria of the gut. The distribution of the leukocytes is structured probably because the immune system has to distinguish between harmful microorganisms, food antigens and the normal gut flora. LÄS MER

  7. 5. Cholera toxin B subunit as a carrier for inducing mucosal immunity and/or peripheral tolerance

    Författare :Carola Rask; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mucosal immunity; tolerance; atopic allergy; cholera toxin B subunit; antibody response; IgE;

    Sammanfattning : When an antigen is introduced via a mucosal route, either immunity or tolerance, or even both may be induced. Both immunity and tolerance are actively induced phenomena and both of them could have important medical implications as well as potential prophylactic or therapeutic applications. LÄS MER