Sökning: "NPM1 type A mutation"
Hittade 2 avhandlingar innehållade orden NPM1 type A mutation.
1. Prognostic markers in pediatric leukemia and mechanisms of KRAS induced leukemogenesis
Sammanfattning : Leukemia results from uncontrolled growth of genetically altered blood cells. Depending on the cell type of origin, the leukemia is defined as T-cell, B-cell, or myeloid and as acute or chronic depending on its characteristics. However, patients with a certain subtype of leukemia (e.g. LÄS MER
2. Measurable residual disease and clonal evolution in acute myeloid leukemia with focus on NPM1-mutations
Sammanfattning : Acute myeloid leukemia (AML) is the most common form of acute leukemia in adults, with mutations in the NPM1 gene occurring in almost one third of all cases. The ability to detect residual leukemia below the resolution of conventional microscopy is crucial for evaluation of relapse risk after therapy. LÄS MER