Sökning: "leukemia"

Visar resultat 1 - 5 av 469 avhandlingar innehållade ordet leukemia.

  1. 1. Perinatal Risk Factors for Childhood Leukemia

    Författare :Estelle Naumburg; Eleni Petridou; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Obstetrics and gynaecology; Childhood leukemia; infant leukemia; leukemia epidemiology; supplementary oxygen; perinatal risk factors; perinatal infection; prenatal ultrasound; prenatal x-ray; Obstetrik och kvinnosjukdomar; Obstetrics and women s diseases; Obstetrik och kvinnosjukdomar; pediatrik; Pediatrics;

    Sammanfattning : The aim of the studies described in this thesis was to assess the association between certain perinatal factors and the risk of childhood lymphatic and myeloid leukemia and infant leukemia. The five studies presented were all conducted in Sweden as population-based case-control studies. LÄS MER

  3. 2. Chronic lymphocytic leukemia : Studies from genetics to epidemiology with focus on the impact of different treatments

    Författare :Mattias Mattsson; Richard Rosenquist; Clemens Wendtner; Uppsala universitet; []
    Nyckelord :Chronic lymphocytic leukemia; genetics; epidemiology; Klinisk genetik; Clinical Genetics; Epidemiologi; Epidemiology;

    Sammanfattning : The progress in our understanding of the biology and pathophysiology of chronic lymphocytic leukemia (CLL), as well as the development of new treatments, necessitates additional research on; (i) the impact of different therapies within subgroups of CLL patients, (ii) solid epidemiological data on the prevalence of CLL and on comorbidities within the CLL population, and (iii) new means of prognostication, as the value of traditional prognostic markers is uncertain when applied to new treatments.In paper I we studied the efficacy of chemo(immuno)therapy in stereotyped subsets #1 and #2. LÄS MER

  4. 3. Chronic lymphocytic leukemia : Studies on cardiovascular disease, biomarkers and subclones

    Författare :Karin Larsson; Martin Höglund; Geir Tjønnfjord; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; : Chronic lymphocytic leukemia; cardiovascular disease; population-based; biomarkers; subclones; Medicinsk vetenskap; Medical Science;

    Sammanfattning : The treatment of Chronic lymphocytic leukemia (CLL) is rapidly changing, with targeted therapies, e.g. Bruton’s tyrosine kinase inhibitors (BTKi), entering the frontline and relapse setting. However, BTKis have significant adverse effects, most notably cardiovascular disease (CVD). LÄS MER

  5. 4. IKAROS and LEUKEMIA

    Författare :Linda Olsson; Avdelningen för klinisk genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pediatric acute lymphoblastic leukemia; relapse; risk-stratifying factors; IKZF1; cooperative changes;

    Sammanfattning : Acute lymphoblastic leukemia (ALL) is characterized by an accumulation of immature lymphoid cells in the bone marrow and is the most common cancer type in children. It is an immunophenotypically, morphologically, clinically, and genetically heterogeneous disorder that comprises several distinct subtypes. LÄS MER

  7. 5. Population-based studies on acute leukemias - lessons from the Swedish Adult Acute Leukemia Registry

    Författare :Lovisa Vennström; Göteborgs universitet; []
    Nyckelord :Acute leukemia; population-based; incidence; survival; acute myeloid leukemia; acute lymphoblastic leukemia; acute promyelocytic leukemia; early death;

    Sammanfattning : Acute leukemia (AL) is a rare, potentially curable, aggressive neoplasm of hematopoietic origin. AL is a heterogeneous disease and is further subdivided according to clinical and biological features. LÄS MER