Sökning: "Multivariate Modelling"

Visar resultat 1 - 5 av 88 avhandlingar innehållade orden Multivariate Modelling.

  1. 1. Modelling and prediction of drug transport processes with experimental and calculated molecular properties : A multivariate approach

    Författare :Thomas Österberg; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacy; FARMACI; PHARMACY; FARMACI; farmaceutisk farmakologi; Pharmaceutical Pharmacology;

    Sammanfattning : Less than 2% of the lead compounds generated by the pharmaceutical industry enter the exploratory drug-development phase, from which point they stand only a 10% chance of becoming a commercial medicine. A large proportion of the compounds fail due to poor biopharmaceutical properties, such as permeability and solubility. LÄS MER

  3. 2. Deciphering sequence data : A multivariate approach

    Författare :Maria Sandberg Hiltunen; Michael Sjöström; Svante Wold; Lars Ståhle; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Principal properties; amino acids; nucleotides; tRNA; DNA; multivariate data analysis; sequence analysis; QSAR; quantitative sequence activity relationships;

    Sammanfattning : In this thesis, attention has been focused on the quantitative description of nucleic acids, proteins and peptides. The strategy was to use multivariate chemometrical methods for improving the understanding of the complex structural codes of these kinds of biological molecules. LÄS MER

  4. 3. Multivariate Modelling of Energy Markets

    Författare :Veronika Lunina; Nationalekonomiska institutionen; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; energy markets; volatility spillover; skew-Student asymmetric BEKK; volatility impulse response function; temperature; hydrobalance; electricity;

    Sammanfattning : This thesis contributes to the empirical energy finance literature and consists of three research papers. The common denominator for all papers is the multivariate modelling approach, placing the electricity market at the core and delving into its interdependencies on fundamentally related markets and factors. LÄS MER

  5. 4. Continuous monitoring of mineral processes with special focus on tumbling mills : a multivariate approach

    Författare :Kent Tano; Luleå tekniska universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Mineralteknik; Mineral Processing;

    Sammanfattning : Increasing emphasis on productivity and quality control has provided an impetus to research on better methodologies for diagnosis, modelling, monitoring, control and optimisation of mineral process systems. One of the biggest challenges facing the research community is the processing of raw sensor data into meaningful information. LÄS MER

  7. 5. Multivariate processing and modelling of hyphenated metabolite data

    Författare :Pär Jonsson; Michael Sjöström; Royston Goodacre; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Chemometrics; Curve Resolution; GC MS; LC MS; Metabolomics; Metabonomics; Multivariate Analysis and Multivariate Curve Resolution.; Organic chemistry; Organisk kemi;

    Sammanfattning : One trend in the ‘omics’ sciences is the generation of increasing amounts of data, describing complex biological samples. To cope with this and facilitate progress towards reliable diagnostic tools, it is crucial to develop methods for extracting representative and predictive information. LÄS MER