Sökning: "Molekylär neuromodulering"

Hittade 3 avhandlingar innehållade orden Molekylär neuromodulering.

  1. 1. Precision mapping of gene expression and proteins in the brain using gene editing and barcoded viral vectors

    Författare :Martino Avallone; Molekylär neuromodulering; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Gene editing; CRISPR Cas9; Barcodes; AAV; PLA; gene therapy; Parkinson’s disease; single nuclei RNAseq; alpha-synuclein;

    Sammanfattning : The human brain is a masterpiece of intricate design and impeccable functionality. It serves as the ultimate command center for our thoughts, sensations, and actions, which define our very existence. LÄS MER

  3. 2. Development of Spatial Sequencing Methods and Applications for Brain Circuit Repair in Parkinson’s Disease

    Författare :Jana Rajova; Molekylär neuromodulering; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; spatial transcriptomics; Parkinson’s Disease; tissue analysis; in situ sequencing; RCA; method development; pseudotime;

    Sammanfattning : .... LÄS MER

  4. 3. A Glial Role in the Action of Electroconvulsive Therapy

    Författare :Malin Wennström; Enheten för psykiatrisk neuromodulering (PNU); []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Psykiatri; klinisk psykologi; psykosomatik; psychosomatics; clinical psychology; Psychiatry; Hippocampus; Depression; Gliogenesis; Electroconvulsive seizures;

    Sammanfattning : The aim of the current thesis was to investigate glial responses to electroconvulsive seizures (ECS), an animal model of the fast-acting antidepressant treatment electroconvulsive therapy (ECT). Depression, a common and devastating disorder, has in recent years been associated with volumetric changes in prefrontal cortex, hippocampus and amygdala, brain regions known to be implicated in emotional behavior. LÄS MER