Sökning: "Michael Höhle"
Hittade 3 avhandlingar innehållade orden Michael Höhle.
1. Scan Statistics for Space-Time Cluster Detection
Sammanfattning : Scan statistics are used by public health agencies to detect and localize disease outbreaks. This thesis provides an overview of scan statistics in the context of prospective disease surveillance and outbreak detection, presents a novel scan statistic to deal with the type of zero-abundant data that is often encountered in these settings, and—perhaps most importantly—implements this and other scan statistics in a freely available and open source R package. LÄS MER
2. Dynamic Modelling of Communicable and Non-Communicable Diseases
Sammanfattning : This thesis consists of two papers dealing with the stochastic dynamic modelling of one communicable and one non-communicable disease respectively. In the first paper we derive a patient- and organ-specific measure for the estimated negative side effects of radiotherapy using a stochastic logistic birth-death process. LÄS MER
3. Stochastic dynamic modelling and statistical analysis of infectious disease spread and cancer treatment
Sammanfattning : Mathematical models have proven valuable for public health decision makers as they can provide insights into the understanding, control and, ultimately, the prevention of diseases. This thesis contains four manuscripts dealing with stochastic dynamic modelling and statistical analysis of infectious disease spread and optimization of cancer treatment. LÄS MER