Sökning: "Mia Sundström"

Hittade 2 avhandlingar innehållade orden Mia Sundström.

1. 1. B cell deviations and type 1 diabetes in the NOD mouse

   Författare :Mia Sundström; Kristina Lejon; Susanna Cardell; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Type 1 diabetes; Autoimmunity; NOD mouse; Idd; TACI; Immune response; Immune complex; immunologi; Immunology;

   Sammanfattning : Type 1 diabetes (T1D) is a chronic autoimmune disease in which the insulin producing β-cells in the pancreatic islets of Langerhans are selectively attacked by the immune system. The β-cells are destroyed resulting in a reduced or eliminated insulin production, which in turn lead to a high blood glucose level. LÄS MER

3. 2. Immunoglobulin Gene Analysis in Different B cell Lymphomas : With Focus on Cellular Origin and Antigen Selection

   Författare :Mia Thorsélius; Richard Rosenquist Brandell; Christer Sundström; Anders Rosén; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; B cell lymphoma; Immunoglobulin; V gene; somatic hypermutation; antigen selection; quantitative PCR; Genetik; Clinical genetics; Klinisk genetik;

   Sammanfattning : B cell lymphoma (BCL) comprises a biologically and clinically heterogeneous group of tumors deriving from different stages of B cell development. The immunoglobulin (Ig) variable heavy chain (VH) gene rearrangement is unique for each BCL and can be used to reveal cellular origin, to study signs of antigen selection and to quantify tumor cell load. LÄS MER