Sökning: "Lymphoproliferative diseases"

Visar resultat 1 - 5 av 15 avhandlingar innehållade orden Lymphoproliferative diseases.

1. 1. Immune Complex Regulated Cytokine Production in Rheumatic and Lymphoproliferative Diseases

   Författare :Linda Mathsson; Johan Rönnelid; Bo Nilsson; Ann Kari Lefvert; Uppsala universitet; []
   Nyckelord :Immunology; Immune complex; Cytokines; Rheumatic diseases; Lymphoproliferative diseases; Immunologi;

   Sammanfattning : Immune complexes (ICs) are produced during normal immune responses and facilitate clearance of foreign antigens. ICs not efficiently cleared from the circulation can cause tissue damage. This might happen if ICs are formed with autoantibodies and autoantigens. LÄS MER

3. 2. Genetics of primary immunodeficiency diseases

   Författare :Javad Mohammadi; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :HLA Antigens; IgA deficiency; Common variable immunodeficiency; immunogenetics; immunodeficiency; TACI;

   Sammanfattning : Selective IgA deficiency (IgAD) (serum IgA concentration of T), which abolished expression of the TACI molecule. In addition, we found the previously recognized C104R and C172Y mutations in a heterozygous form in 2 patients with CVID and one, novel, heterozygous P42T mutation. LÄS MER

4. 3. Molecular characterization of the hepatitis C virus core protein

   Författare :Priya Devi; Anders Bergqvist; Björn Olsen; Tanel Punga; Gerald McInerney; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; HCV; core protein; SHP-1; CpG methylation; bisulfite sequencing; NGS; PBMC; Ca2 NFAT; strand-specific RT qPCR; Klinisk virologi; Clinical Virology; Infektionssjukdomar; Infectious Diseases; Mikrobiologi; Microbiology; Medical Virology; Medicinsk virologi;

   Sammanfattning : Hepatitis C virus (HCV) is an RNA virus that causes chronic infection, which can lead to hepatocellular carcinomas in humans. Besides liver diseases, the chronic HCV infection causes a broad spectrum of extrahepatic complications such as lymphoproliferative, metabolic and autoimmune disorders. LÄS MER

5. 4. Clinical impact of epoetins in the treatment of anemia with special emphasis on patients with lymphoid malignancies. : dosing, iron supplementation and safety

   Författare :Michael Hedenus; Jack Lindh; Anders Österborg; Robert Hast; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; anemia; cancer; lymphoproliferative malignancies; erythropoietin; intravenous iron; safety; Oncology; Onkologi; Oncology; onkologi;

   Sammanfattning : The aim of this thesis was to determine the relevant dose of arbepoetin-alfa (DA) in patients with lymphoproliferative diseases (LPD) and chemotherapy induced anemia (CIA), to study the clinical impact of intravenous (IV) iron supplementation combined with epoetin beta treatment, to identify factors that might predict hemoglobin (Hb) response to treatment with epoetins and to investigate safety of DA.A dose-finding phase II study was able to assess a reasonable DA dose of 2. LÄS MER

7. 5. Hepatitis C virus infection : a nationwide study of associated morbidity and mortality

   Författare :Ann-Sofi Duberg; Erik Bäck; Karl Ekdahl; Rolf Hultcrantz; Anders Blaxhult; Johan Carlson; Örebro universitet; []
   Nyckelord :HCV; hepatitis C; epidemiology; non-Hodgkin s lymphoma; NHL; multiple myeloma; primary liver cancer; HCC; mortality; inpatient care; hospitalization; MEDICINE; MEDICIN; Infektionssjukdomar; Infectious Diseases; Epidemiology; Epidemiologi; Medicin; Medicine;

   Sammanfattning : The hepatitis C virus (HCV) was characterised in 1989. HCV was transmitted through transfusion of blood/blood products, but injection drug use is now the most common route of transmission. LÄS MER