Sökning: "Long term-potentiation"

Visar resultat 11 - 15 av 24 avhandlingar innehållade orden Long term-potentiation.

  1. 11. Plasticity and variation of synaptic responses in hippocampus. Role of AMPA and NMDA receptors

    Författare :Yin-Ping Niu; Göteborgs universitet; []
    Nyckelord :learning and memory; synaptic plasticity; hippocampus; synapse; AMPA receptor; NMDA receptor; LTP; LTD; CV; TFS;

    Sammanfattning : It is generally believed that synaptic plasticity in the central nervous system may underlie learning and memory as well as neuronal development. The most wellstudied examples of such synaptic plasticity are long-term potentiation (LTP) andlong-term depression (LTD). LÄS MER

  3. 12. Experimental nerve injury : induced pain : mechanisms and modulation

    Författare :Johan Wallin; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Chronic nerve injury-induced pain presents a therapeutic challenge since such pain is often resistant to conventional analgesic drugs including opioids. Better knowledge of the pathophysiological mechanisms underlying nerve injuryinduced pain is necessary to develop new and more efficacious therapies. LÄS MER

  4. 13. Non-linear synaptic integration on dendrites of striatal medium-spiny neuron : a computational study

    Författare :Kai Du; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Striatum is the main input nucleus of basal ganglia. Medium-spiny neurons (MSNs), the principal neurons of the striatum, receive convergent excitatory inputs from cortex and thalamus, thus “gate” the information flow to the basal ganglia. LÄS MER

  5. 14. The significance of blood vessels in organogenesis and cadherins in exploratory behaviour

    Författare :Josefina Edsbagge; Göteborgs universitet; []
    Nyckelord :pancreas; sphingosine-1-phosphate; endothelium; epithelial-to-mesenchymal interactions; ; Cre loxP-system; cadherins; rearing;

    Sammanfattning : Organogenesis of epithelial organs requires interaction between epithelial andmesenchymal tissues. In pancreas development three different mesenchymal derivedstructures, the notochord, the endothelial cells and the splanchnic mesenchyme inducespecification, growth and further differentiation of the pancreatic epithelium. LÄS MER

  7. 15. Molecular mechanisms of synaptic transmission and plasticity in spinal sensory pathways

    Författare :Max Larsson; Neurofysiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neurophysiology; neuropsychology; Neurology; electron microscopy; synaptic plasticity; synapse; pain; spinal cord; hyperalgesia; Neurologi; neuropsykologi; neurofysiologi;

    Sammanfattning : An intense, potentially tissue-damaging (noxious) stimulus may lead to enhanced pain sensation of subsequent noxious stimuli (hyperalgesia) and to the perceiving of innocuous stimuli as painful (allodynia). This is thought to result to a large extent from strengthening of synapses established by primary afferent fibers onto spinal cord dorsal horn neurons. LÄS MER