Sökning: "Long term-potentiation"
Visar resultat 21 - 24 av 24 avhandlingar innehållade orden Long term-potentiation.
21. Pharmacological and environmental modulations of the rat glutamatergic system
Sammanfattning : Glutamate is the principal excitatory neurotransmitter in the central nervous system and it is implicated in neural transmission, learning, memory processes and neuronal plasticity. In the glutamatergic synapse two main components are present; the glutamate receptors and the glutamate transporters. LÄS MER
22. Drug discovery targeting non-amyloid pathways in Alzheimer’s disease
Sammanfattning : Alzheimer’s disease (AD) is the most common form of dementia with almost 50 million people affected and unfortunately, no cure or treatment to halt the disease progression is available. In the hereditary forms of AD, an overproduction of amyloid β (Aβ) and the Aβ plaque formation are the basis for the amyloid hypothesis of AD, while several additional factors seem to influence the likelihood to develop sporadic forms of AD. LÄS MER
23. Striatal glutamatergic neurotransmission and plasticity in Parkinson’s disease and aging
Sammanfattning : Parkinson's disease (PD) is a devastating neurodegenerative disorder with aging as the main risk factor. PD is characterized by severe movement disturbances but is also associated with non-motor symptoms. LÄS MER
24. Modulation of pain by immune factors : a study on interferon-g and its receptor in nociceptive transmission
Sammanfattning : Immune cytokines have been implicated as important neuromodulators, contributing to neuronal plasticity both in the adult and developing nervous system. In addition, they have been assigned a potential role in the generation of pathological pain, which may occur as a severe symptom following disease states in the nervous system. LÄS MER
