Sökning: "LDL-oxidation"

Visar resultat 6 - 9 av 9 avhandlingar innehållade ordet LDL-oxidation.

  1. 6. Immune Responses Aginst Aldehyde Modified Extracellular Matrix in Atherosclerosis

    Författare :Pontus Dunér; Kardiovaskulär forskning - immunitet och ateroskleros; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PlaqueMalondialdehydeAtherosclerosisAutoantibodiesExtracellular MatrixFibronectinLamininoxidized LDLT regulatory cellsAlum;

    Sammanfattning : Atherosclerosis is a chronic inflammatory disease and the leading cause of myocardial infarction and stroke. Accumulation, aggregation and subsequent oxidation of LDL in the arterial wall are considered as key events in the development of atherosclerosis. LÄS MER

  3. 7. Iron and macrophages in atherogenesis

    Författare :Xi Ming Yuan; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Oxidation of low density lipoprotein (LDL) may result in its uptake by macrophages and ensuing foam cell formation. Thus, oxidised LDL may play an important role in atherogenesis. Extensive in vitro evidences are in favour of the notion that LDL oxidation by cells present in atherosclerotic plaques requires the presence of transition metals. LÄS MER

  4. 8. Low-Density Lipoprotein Oxidation and Renal Dysfunction : New Markers of Poor Prognosis in Patients with Unstable Coronary Artery Disease

    Författare :Nina Johnston; Lars Wallentin; Tomas Jernberg; Agneta Siegbahn; Lena Jonasson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; myocardial infarction; unstable angina; oxidized low-density lipoprotein; renal function; prognosis; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin;

    Sammanfattning : In patients with unstable coronary artery disease (CAD) biochemical markers are emerging as useful tools in clinical management. In this thesis we studied the use of markers of low-density lipoprotein (LDL) oxidation and renal function. LÄS MER

  5. 9. Platelet-activating factor and lysophospatidylcholine in oxidized low density lipoprotein-mediated immune activation

    Författare :Yihui Huang; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :atherosclerosis; oxidized LDL; platelet-activating factor PAF ; Iysophosphatidylcholine LPC ; anti-MHC class II antibodies; antibody; T cells; cytokine; IFN-[gamma]; IL-6; IL-4; TNF-[alpha]; a PAF specific receptor antagonist-WEB2170;

    Sammanfattning : Inflammation is a risk factor for development of cardiovascular disease, as in addition to known risk factors such as hypertension, hyperlipidemia, smoking and diabetes. Patients with inflammatory diseases including SLE have an enhanced risk of cardiovascular disease. LÄS MER