Sökning: "Helena Lindmark"

Hittade 3 avhandlingar innehållade orden Helena Lindmark.

  1. 1. Bioactive Proteins in Bovine Milk - Studies on Glutathione Peroxidase, Lactoferrin and Immunoglobulins

    Författare :Helena Lindmark Månsson; Kemiska institutionen; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; General biomedical sciences; Biokemisk teknik; Biochemical technology; thermal stability; milk processability; selenium; antioxidants; immunoglobulin; lactoferrin; Milk; glutathione peroxidase; Biomedicinska vetenskaper allmänt ; Biochemistry; Metabolism; Biokemi; metabolism;

    Sammanfattning : Many proteins in bovine milk exhibit specific biological activity in addition to their established nutritional value as source of protein. Examples of such bioactive proteins are extracellular glutathione peroxidase, lactoferrin and immunoglobulins. LÄS MER

  3. 2. Bridging the gap between clinical trials and clinical practice : sacubitril-valsartan in heart failure as a model

    Författare :Helena Norberg; Krister Lindmark; Ellinor Bergdahl; Eva-Lotta Glader; Björn Wettermark; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Systematic implementation; healthcare quality improvement; chronic disease management; heart failure; sacubitril-valsartan; real-world population; sex differences; kardiologi; Cardiology;

    Sammanfattning : When novel treatments prove more effective than standard therapies, a swift and effective implementation is needed to reach cost-effectiveness and to benefit eligible patients. Meanwhile, women and elderly are often under-represented in clinical trials, which creates a knowledge gap on how to optimize treatment in clinical practice. LÄS MER

  4. 3. Mineralocorticoid receptor antagonists in heart failure : exploring the gap between guideline-directed medical therapy and real-world practice

    Författare :Anna Jonsson Holmdahl; Krister Lindmark; Helena Norberg; Ellinor Bergdahl; Fredrik Valham; Niklas Bergh; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Heart failure; Mineralocorticoid receptor antagonists; estimated glomerular filtration rate; hyperkalemia; impaired renal function; worsening renal function; guideline-directed medical therapy; kardiologi; Cardiology;

    Sammanfattning : Heart failure is the possible end-result of a variety of different diseases, where ischemic heart disease and hypertension are the most common causes in high income countries. In Sweden, heart failure has a prevalence of 2% in the adult population and rises to over 10% among people over 70 years of age. The 5-year all-cause mortality is about 50%. LÄS MER