Sökning: "Gunilla Olivecrona"
Visar resultat 1 - 5 av 9 avhandlingar innehållade orden Gunilla Olivecrona.
1. Lipoprotein lipase : mechanism for adaptation of activity to the nutritional state
Sammanfattning : Lipoprotein lipase (LPL) is an enzyme to hydrolyze triglycerides in lipoproteins and thereby make the fatty acids available for cellular metabolic reactions. Short-term fasting down-regulates LPL activity in adipose tissue. This regulation is through post-translational mechanism. LÄS MER
2. Regulation of Lipoprotein Lipase Activity : an In-vitro Study of a Complex and Dynamic System
Sammanfattning : The progress of human society outpaces our biological evolution, and this brings unexpected health problems. The industrial revolution brought up dramatic changes in nutrition and lifestyle – we are increasingly shifting towards a nutrient-rich Western-patterned diet and to a sedentary lifestyle. LÄS MER
3. Endogenous and exogenous factors affecting lipoprotein lipase activity
Sammanfattning : Individuals with high levels of plasma triglycerides are at high risk to develop cardiovascular disease (CVD), currently one of the major causes of death worldwide. Recent epidemiological studies show that loss-of-function mutations in the APOC3 gene lower plasma triglyceride levels and reduce the incidence of coronary artery disease. LÄS MER
4. Lipoprotein lipase activity is reduced in dialysis patients. Studies on possible causal factors
Sammanfattning : Cardiovascular disease is a major cause of mortality and morbidity in patients on chronic haemodialysis (HD). One main contributing factor is renal dyslipidaemia, characterized by an impaired catabolism of triglyceride (TG)-rich lipoproteins with accumulation of atherogenic remnant particles. LÄS MER
5. Insights into the relationship between coronary calcification and atherosclerosis risk factors
Sammanfattning : Introduction Coronary artery disease (CAD) is the most common cause of death in Europe and North America and early detection of atherosclerosis is a clinical priority. Diagnosis of CAD remains conventional angiography, although recent technology has introduced non-invasive imaging of coronary arteries using computed tomographic coronary angiography (CTCA), which enables the detection and quantification of coronary artery calcification (CAC). LÄS MER