Sökning: "Groucho"

Hittade 3 avhandlingar innehållade ordet Groucho.

  1. 1. Epstein-Barr virus nuclear antigen 1, Oct and Groucho/TLE in control of promoter regulation

    Författare :Jenny Almqvist; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :EBV; Oct-1; Oct-2; Groucho; TLE; transcription; repression; latency;

    Sammanfattning : The human herpes virus Epstein-Barr virus (EBV) is carried by approximately 95% of the adult population. It can form a lifelong latent infection in the B-cells by avoiding our immune system. A latent EBV infection is usually asymptomatic but a few EBV associated cancer forms has been described (e.g. LÄS MER

  3. 2. Transcriptional mechanisms directing terminal differentiation of B lineage cells

    Författare :Ylva Linderson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The interaction between the B cell receptor (surface immunoglobulin) and its ligand (antigen) can result in extensive cell growth and induction of differentiation. The terminally differentiated B cell fulfills the ultimate purpose of B cell existence: to secret antibodies in order to protect the organism against invading pathogens. LÄS MER

  4. 3. The role of transcriptional repression in Shh signalling and patterning of the ventral neural tube

    Författare :Madelen Persson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : From flies to humans, members of the Hedgehog (Hh) family of secreted signalling molecules play a vital role in determining cell fate and patterning during embryonic development. In vertebrates, Sonic Hedgehog (Shh) act in a graded manner to establish distinct neural progenitor populations at different concentration thresholds in the ventral neural tube. LÄS MER