Sökning: "FENO"

Visar resultat 16 - 20 av 20 avhandlingar innehållade ordet FENO.

  1. 16. Clinical studies on the role of eicosanoids in the asthmatic airway inflammation

    Författare :Kameran Daham; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The underlying mechanisms in the asthmatic airway inflammation involve the interaction between different cells and mediators that consequently result in different clinical phenotypes. The aim of this thesis was to investigate the impact of inflammatory mediators, with emphasis on eicosanoids, on the inflammatory and functional airway responses under basal and triggered conditions in subjects with asthma, in particular ASA/NSAID-intolerant and allergic phenotypes. LÄS MER

  3. 17. Exhaled nitric oxide in extreme environments

    Författare :Tryggve Hemmingsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Exhaled nitric oxide; hand-held instrument; electrochemical detector; microgravity; International Space Station; high altitude; hypobaric hypoxia; normobaric hypoxia; backdiffusion;

    Sammanfattning : Exhaled nitric oxide (NO) is a useful marker for lower airway inflammation. Since NO was found to be a component of an exhaled breath in the early 1990´s, the Fractional Exhaled Nitric Oxide (FENO 50) measurement is now well accepted among clinicians as a complementary test in the management of asthma. LÄS MER

  4. 18. Investigating problematic severe asthma in children : a translational approach

    Författare :Jon R Konradsen; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Children with problematic severe asthma (PA) have persistent symptoms and/or severe exacerbations despite treatment with high doses of currently available asthma medications. The term PA includes children who are difficult to treat due to unidentified exacerbating factors (e.g. LÄS MER

  5. 19. Exploring eicosanoids as biomarkers in severe chronic rhinosinusitis with nasal polyps

    Författare :Axel Nordström; Maria Kumlin; Marie Svedberg; Mattias Jangard; Michael Ryott; Gunnar Nilsson; Sophiahemmet Högskola; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Chronic rhinosinusitis (CRS) is one of the most common inflammatory chronic conditions, leading to a persistent nasal congestion, nasal discharge, and a loss of smell. Despite sinus surgery and frequent use of oral corticosteroids, a large proportion of individuals with CRS are difficult to treat and have recurrent inflammation. LÄS MER

  7. 20. Factors associated with preschool wheeze developing into school-age asthma

    Författare :Idun Holmdahl; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Preschool wheeze affects one third of all toddlers up to the age of three years and half of the children before six years of age. Approximately one third of these children will develop asthma in school age, and several risk factors have been proposed. LÄS MER