Sökning: "Diabetes - molekylär metabolism"

Visar resultat 1 - 5 av 32 avhandlingar innehållade orden Diabetes - molekylär metabolism.

  1. 1. The role of galectin-1 in type 2 diabetes. Clinical and experimental studies

    Författare :Emanuel Fryk; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; galectin-1; type 2 diabetes; human; adipose tissue; metabolism;

    Sammanfattning : Aim: The purpose of this thesis was to identify a new agent in the subcutaneous adipose tissue and assess its clinical potential in the context of type 2 diabetes. Study I: Through a combination of microdialysis and mass-spectrometry, we found increased galectin-1 levels in the subcutaneous adipose tissue in a small experimental study of 15 men with and without type 2 diabetes. LÄS MER

  3. 2. On the role of gut microbiota in intestinal physiology and hepatic metabolism

    Författare :Mattias Bergentall; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; microbiota; metabolism;

    Sammanfattning : The gut microbiota, a complex and dynamic community of microbes in the mammalian gut, has coevolved with us for ample time providing mutual benefits. However, mechanistic knowledge of these has been limited, but are now becoming increasingly clear. LÄS MER

  4. 3. Genetic and phenotypic discordance in cardiometabolic diseases

    Författare :Daniel Coral; Genetisk och molekylär epidemiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Obesity; Diabetes; Cardiovascular disease; Genome-wide association studies; Heterogeneity;

    Sammanfattning : Cardiometabolic conditions such as obesity and type 2 diabetes (T2D) are among the first causes of death globally, and the number of people affected is rapidly increasing. Both conditions are intricately connected and are associated with many life-threatening cardiovascular disease (CVD). LÄS MER

  5. 4. Control of metabolism and hormone secretion from pancreatic alpha and beta cells

    Författare :Jelena Stamenkovic; Diabetes - molekylär metabolism; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CLOCK genes; insulin; glucagon; metabolites; mitochondria; knock out;

    Sammanfattning : Type 2 Diabetes (T2D) is a multifactorial disease, which has made it difficult to resolve its pathophysiology. We investigated processes that could contribute to the development of T2D. LÄS MER

  7. 5. Berries in Prevention of Metabolic Disease – focus on obesity, diabetes and gut microbiota

    Författare :Lovisa Heyman; Molekylär nutrition; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; obesity; type 2 diabetes; berries; low-grade inflammation; gut microbiota; hepatic steatosis; gene expression; DNA methylation; lingonberry; blackcurrant; bilberry; açai;

    Sammanfattning : The increasing prevalence of obesity is a worldwide health problem closely linked to diet and lifestyle factors. Obesity is associated with increased risk of several metabolic disorders including insulin resistance, nonalcoholic fatty liver disease and type 2 diabetes. LÄS MER