Sökning: "Developmental Neurosciences"

Visar resultat 21 - 25 av 45 avhandlingar innehållade orden Developmental Neurosciences.

  1. 21. Genetic Mechanisms Regulating the Spatiotemporal Modulation of Proliferation Rate and Mode in Neural Progenitors and Daughter Cells during Embryonic CNS Development

    Författare :Behzad Yaghmaeian Salmani; Stefan Thor; Jan-Ingvar Jönsson; Mattias Mannervik; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : The central nervous system (CNS) is a hallmark feature of animals with a bilateral symmetry: bilateria and can be sub-divided into the brain and nerve cord. One of the prominent properties of the CNS across bilateria is the discernible expansion of its anterior part (brain) compared with the posterior one (nerve cord). LÄS MER

  3. 22. Generating GABAergic interneurons through reprogramming and differentiation strategies : English

    Författare :Andreas Bruzelius; Regenerativ neurofysiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; interneurons; neuronal reprogramming; glial progenitor cells; neuronal differentiation; human embryonic stem cells; induced neurons; somatostatin; parvalbumin;

    Sammanfattning : In recent years reprogramming techniques, differentiation protocols, and sequencing analysis have opened a field for generating and studying human-derived neurons with greater potential than ever before. This has generated a large number of studies with the goal of deriving bona fide neurons. LÄS MER

  4. 23. Crossing the Midline : Locomotor Neuronal Circuitry Formation

    Författare :Fatima Memic; Klas Kullander; Avihu Klar; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CPG; CIN; neuronal network; locomotion; left-right alternation;

    Sammanfattning : Networks at various levels of the nervous system coordinate different motor patterns such as respiration, eye or hand movements and locomotion. Intrinsic rhythm-generating networks that are located in the spinal cord generate motor behaviors that underlie locomotion in vertebrates. LÄS MER

  5. 24. Towards Better Understanding of Etiological Mechanisms at the Neuromuscular Junction

    Författare :Evgenii Bogatikov; Anna Rostedt Punga; Klas Kullander; Viktorija Kenina; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neuromuscular junction; Muscle cells; Microelectrode array; MicroRNA; Clinical Neurophysiology; Klinisk neurofysiologi; Biomedical Laboratory Science; Biomedicinsk laboratorievetenskap;

    Sammanfattning : The neuromuscular junction (NMJ) serves as a model for understanding the mechanisms that determine communication between neurons and their target cells. Disorders of the NMJ can be either autoimmune or genetic (hereditary). LÄS MER

  7. 25. Markers and mechanisms of abnormal neurovascular development in the preterm infant

    Författare :William Hellström; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neonatology; Brain development; Extremely preterm infant; Brain volume; Retinopathy of prematurity; Insulin-like growth factor 1; Neurofilament light; Neurodevelopment;

    Sammanfattning : Background: The extremely preterm infant is at risk of lifelong neurodevelopmental impairments due to brain injuries or abnormal neurovascular development. Mechanisms are largely unknown and biomarkers for adverse outcomes are sparse. LÄS MER