Sökning: "interneurons"
Visar resultat 1 - 5 av 113 avhandlingar innehållade ordet interneurons.
1. Generating GABAergic interneurons through reprogramming and differentiation strategies : English
Sammanfattning : In recent years reprogramming techniques, differentiation protocols, and sequencing analysis have opened a field for generating and studying human-derived neurons with greater potential than ever before. This has generated a large number of studies with the goal of deriving bona fide neurons. LÄS MER
2. Endogenous modulators of hyperexcitability in epilepsy: electrophysiological and optogenetic delineation of neuropeptide Y mechanisms in interneurons
Sammanfattning : Epilepsy is one of the most common neurological disorders worldwide, affecting 1% of the general population, and is characterized by a predisposition for the generation of epileptic seizures. Despite having several different aetiologies, a common underlying cause of epilepsy seems to be an acquired imbalance between excitatory and inhibitory circuits in the brain, which leads to hyperexcitability and appearance of seizures. LÄS MER
3. Diving into the zebrafish locomotor network : A study on dI6 interneurons
Sammanfattning : The generation and coordination of locomotion comprise of inhibitory and excitatory interneurons that govern motor neuron output to muscles. This neuronal network is known as the central pattern generator (CPG). Spinal inhibitory interneurons that originate from the dI6 population play a crucial role in the coordination of locomotor output. LÄS MER
4. Enhancing neuronal inhibition by cell and gene therapy as a novel treatment for Epilepsy
Sammanfattning : Epilepsy is a family of heterogeneous and multifactorial neurological disorders, unified by the occurrence of spontaneous recurrent seizures. Overall, it affects 50 million people worldwide of all ages and genders. LÄS MER
5. On the Mechanisms Behind Hippocampal Theta Oscillations : The role of OLMα2 interneurons
Sammanfattning : Theta activity is one of the most prominent rhythms in the brain and appears to be conserved among mammals. These 4-12 Hz oscillations have been predominantly studied in the dorsal hippocampus where they are correlated with a broad range of voluntary and exploratory behaviors. LÄS MER