Sökning: "Anna Månberg"

Hittade 4 avhandlingar innehållade orden Anna Månberg.

  1. 1. Multiplexed antibody-based protein profiling in the pursuit of CSF biomarkers for neurodegenerative diseases

    Författare :Sofia Bergström; Peter Nilsson; Anna Månberg; Markus Otto; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Protein profiling; suspension bead array; cerebrospinal fluid; biomarker discovery; proteomics; Bioteknologi; Biotechnology;

    Sammanfattning : There is a desire for a transition from generic treatments designed for the average patient, towards more individual-based precision medicine. An increased knowledge about disease pathophysiology on a molecular level would be beneficial for this transition. LÄS MER

  3. 2. On the analysis of antibody repertoires

    Författare :August Jernbom Falk; Peter Nilsson; Anna Månberg; Albert J.R. Heck; KTH; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; antibody repertoire; autoantibodies; serology; microarray; bead array; affinity proteomics; psychosis; SARS-CoV-2; COVID-19; post-COVID-19 condition; immunoglobulin; IgG; Biotechnology; Bioteknologi;

    Sammanfattning : The antibody repertoire is the ensemble of antibodies found in an individual at a given time. It displays high heterogeneity between individuals while being both largely temporally stable within an individual and rapidly responsive to immunological challenge. LÄS MER

  4. 3. On the profiling of autoantibodies in psychiatric disorders

    Författare :David Just; Peter Nilsson; Anna Månberg; Jochen M. Schwenk; Angela Vincent; KTH; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; affinity proteomics; microarrays; suspension bead array; autoantibodies; autoimmunity; psychiatric disorders; schizophrenia;

    Sammanfattning : There is a great need to increase our understanding of diseases affecting the brain and their underlying pathogenic mechanisms. To address this need, the work presented in this thesis applied affinity based proteomic techniques to profile proteins, and to investigate protein profiles and the autoantibody repertoire in brain related disorders. LÄS MER

  5. 4. Dementia Proteomics

    Författare :Julia Remnestål; Peter Nilsson; Anna Månberg; Pieter Jelle Visser; KTH; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Dementia; Proteomics; Alzheimer s disease; Frontotemporal dementia; Antibody array; Suspension bead array; Cerebrospinal fluid; Protein profiling; Biomarker discovery; Bioteknologi; Biotechnology;

    Sammanfattning : The term dementia encompass a number of conditions arising as a consequence of tissue degeneration in the brain. This degeneration is caused by molecular events occurring on a cellular level including inflammation, defective waste disposal and accumulation of insoluble proteins and peptides. LÄS MER