Sökning: "Acute lymphoblastic leukaemia"

Visar resultat 21 - 25 av 27 avhandlingar innehållade orden Acute lymphoblastic leukaemia.

  1. 21. Childhood brain tumours : health and function in adult survivors and parental fears

    Författare :Malin Anclair; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Childhood brain tumours; adult survivors; health-related late effects; parental fears;

    Sammanfattning : The general aim of the present research was to investigate health and functional ability of patients treated for childhood brain tumour and systematically examine parental fears after a child s brain tumour. The aims were realised through two part-studies. LÄS MER

  3. 22. Reconstitution of the B-cell repertoire following allogeneic bone marrow transplantation

    Författare :Ingrid Näsman Björk; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :B cell repertoire allogeneic bone marrow transplantation immune reconstitution immunoglobulin genes serum immunoglobulin;

    Sammanfattning : Allogeneic bone marrow transplantation (BMT) is an established therapy for patients with a variety of haematological malignancies. Patients undergoing BMT often suffer from severe infections that can be partly explained by humoral immune deficiency. LÄS MER

  4. 23. Pharmacological studies on uptake, metabolism, and resistance to anti-cancer drugs : insights into the treatment of leukemia

    Författare :Hazhar Karim; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Leukemia is blood cancer that begins in the bone marrow and characterized by abnormal production of white blood cells. Due to advances in treatment, there has been a dramatic increase in survival rate for patients with different types of leukemia. LÄS MER

  5. 24. Pharmacogenetic studies of thiopurines : focus on thiopurine methyltransferase

    Författare :Malin Lindqvist Appell; Michel Eichelbaum; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Pharmacogenetics represents the study ofvariability in drug response due to genetic variations. The thiopurines (6-mercaptopurine, 6-thioguanine and azathioprine) are prodrugs which require metabolic transformation to exert effect. LÄS MER

  7. 25. Dimension Reduction and Signal Decomposition for Genotype–Phenotype Relations

    Författare :Rasmus Perby Henningsson; Matematik LTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Matematik; Bioinformatik; Dimensionsreduktion; Computational mathematics; Bioinformatics; Dimension reduction;

    Sammanfattning : Over the last few decades, DNA sequencing has developed from costing billions of dollars to get the complete sequence of the human genome, to being a routine procedure performed in labs all around the world. This has transformed the field of experimental biology since measurements can be done at a level of detail that was not possible before. LÄS MER