Sökning: "therapeutic relationship"

Visar resultat 26 - 30 av 167 avhandlingar innehållade orden therapeutic relationship.

1. 26. Adherence to Antidepressant Medication

   Författare :Ann-Charlotte Åkerblad; Lisa Ekselius; Ingvar Krakau; Uppsala universitet; []
   Nyckelord :Psychiatry; adherence; depression; randomised controlled trial; intervention; therapeutic drug monitoring; personality; health status; health care utilisation; Psykiatri;

   Sammanfattning : Non-adherence to medication is a major obstacle in the treatment of depression. The objectives of the present study were to explore the effect of two interventions aiming to increase antidepressant treatment adherence, and to examine long-term consequences and costs of depression in adherent and non-adherent primary care patients. LÄS MER

3. 27. Fatal attraction : the relationship between patients and their eating disorders, an interpersonal and attachment perspective

   Författare :Emma Forsén Mantilla; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Eating disorders are severe psychiatric illnesses, causing immense suffering for patients, but also for their families and friends. Ambivalence about change and treatment resistance are common, and relapse rates are high. LÄS MER

4. 28. Pharmacometric Approaches to Improve Dose Individualization Methods in Hemophilia A

   Författare :João A. Abrantes; Mats Karlsson; Elisabet I. Nielsen; Siv Jönsson; Ron Mathôt; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Bayesian forecasting; coagulation factor VIII; dose adaptation; hemophilia haemophilia A; inter-occasion variability; NONMEM; pharmacodynamics; pharmacokinetics; pharmacometrics; therapeutic drug monitoring; Farmaceutisk vetenskap; Pharmaceutical Science;

   Sammanfattning : Hemophilia A is a bleeding disorder caused by the lack of functional coagulation factor VIII (FVIII). The overall aim of this thesis was to improve dose individualization of FVIII replacement therapy in hemophilia A using pharmacometric approaches. LÄS MER

5. 29. Inhibitors Targeting Insulin-Regulated Aminopeptidase (IRAP) : Identification, Synthesis and Evaluation

   Författare :Karin Engen; Mats Larhed; Mikael Elofsson; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; compound screening; insulin-regulated aminopeptidase; IRAP; inhibitors; cognitive disorders; spiro-oxindole; quinazolinone; imidazopyridine; medicinal chemistry; structure-activity relationship; microwave heating; Medicinal Chemistry; Läkemedelskemi;

   Sammanfattning : Insulin-regulated aminopeptidase (IRAP) has emerged as a potential new therapeutic target for treatment of cognitive disorders. Inhibition of the enzymatic activity facilitates cognition in rodents. LÄS MER

7. 30. Pharmacometric Models to Improve the Treatment and Development of Drugs against Tuberculosis

   Författare :Robin J. Svensson; Ulrika S H Simonsson; Mats O Karlsson; Andreas Krause; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacokinetics; Pharmacodynamics; Biomarkers; Rifampicin; Clofazimine; Therapeutic drug monitoring; Time-to-event; Time-to-positivity; Molecular bacterial load assay; Farmaceutisk vetenskap; Pharmaceutical Science;

   Sammanfattning : With 10 million new infections yearly, tuberculosis has a major impact on the human well-being of the world. Most patients have infections susceptible to a first-line treatment with a treatment success rate of 80%, a number that can potentially be improved by optimising the first-line treatment. LÄS MER