Sökning: "imidazopyridine"

Hittade 2 avhandlingar innehållade ordet imidazopyridine.

  1. 1. Inhibitors Targeting Insulin-Regulated Aminopeptidase (IRAP) : Identification, Synthesis and Evaluation

    Författare :Karin Engen; Mats Larhed; Mikael Elofsson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; compound screening; insulin-regulated aminopeptidase; IRAP; inhibitors; cognitive disorders; spiro-oxindole; quinazolinone; imidazopyridine; medicinal chemistry; structure-activity relationship; microwave heating; Medicinal Chemistry; Läkemedelskemi;

    Sammanfattning : Insulin-regulated aminopeptidase (IRAP) has emerged as a potential new therapeutic target for treatment of cognitive disorders. Inhibition of the enzymatic activity facilitates cognition in rodents. LÄS MER

  3. 2. Synthesis of sulfur and selenium heterocycles, including derivatives of imidazopyridine and benzimidazole

    Författare :Malin Björk; Spiros Grivas; Christopher A. Ramsden; Södertörns högskola; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Aminoimidazoazaarenes; thienomethyleneimidazolinones; imidazo[4; 5b]pyridines; Friedländer; imidazo[4; 5-e]-2; 1; 3-benzoselenadiazoles; 2-aminobenzimidazoles. palladium catalyzed coupling reactions.;

    Sammanfattning : The chemistry developed in this thesis can be divided into two parts. The first part, which is the major part of the thesis, contains syntheses towards analogues to mutagenic heterocyclic amines found in e.g. meat fried at high temperatures. LÄS MER