Sökning: "solid-phase synthesis"
Visar resultat 16 - 20 av 82 avhandlingar innehållade orden solid-phase synthesis.
16. Studies in solid phase peptide synthesis and self-assembly of cyclic peptides
Sammanfattning : .... LÄS MER
17. Improved solid phase synthesis of apamin, the principal neurotoxin of bee venom : structure-function studies based on synthetic analogues
Sammanfattning : .... LÄS MER
18. Applications of multi-component condensations and development of polyamine synthesis on solid-phase
Sammanfattning : Solid-phase synthesis of small non-polymeric molecules has become increasingly important as a tool in the development of pharmacologically active compounds. Of particular interest are the syntheses of compounds with low molecular weight, low polarity and a reduced flexibility of the functional groups, i.e. LÄS MER
19. Studies aimed at improving the H-phosphonate approach for solid phase oligonucleotide synthesis
Sammanfattning : .... LÄS MER
20. Design and Synthesis of Potential Aminoacyl-tRNA Synthetase Inhibitors
Sammanfattning : Aminoacyl-tRNA synthetases (aaRSs) are essential enzymes present in all living organisms, their catalytic activity is involved in the translation of the genetic code into functional proteins and they are potential targets for anti-infective agents. The first step in the biosynthetic pathway catalysed by aaRSs consists of activation of the corresponding amino acid by the reaction with ATP to form an aminoacyl-adenylate (aa-AMP), the key intermediate in the biosynthesis of proteins. LÄS MER