Sökning: "small vessel disease"
Visar resultat 1 - 5 av 58 avhandlingar innehållade orden small vessel disease.
1. Magnetic resonance imaging markers of cerebral small vessel disease in an elderly population – association with cardiovascular disease and cognitive function
Sammanfattning : Cerebral small vessel disease (SVD) is identifiable by clinical, neuroimaging, neuropathological and cognitive findings.The aim of this thesis was to assess SVD and cerebral perfusion on magnetic resonance imaging (MRI) in a 75-year-old population and compare the findings with scars of myocardial infarctions, cardiovascular risk markers and cognitive function. LÄS MER
2. Comorbidity and vascular risk factors associated with idiopathic normal pressure hydrocephalus : the INPH-CRasH Study
Sammanfattning : Idiopathic normal pressure hydrocephalus (INPH) is a dementia treatable by insertion of a cerebrospinal fluid shunt. It has been suggested that INPH has similar pathophysiological mechanisms as cerebrovascular disease, but the vascular risk factor (VRF) profile of INPH patients has not been assessed using a modern epidemiological approach. LÄS MER
3. Microvascular brain raspberries: A clinicopathological study
Sammanfattning : .... LÄS MER
4. CADASIL : a pure model for studying cerebral small vessel disease
Sammanfattning : Cerebral autosomal dominant arteriopathy with subcortical infarct and leukoencephalopathy (CADASIL) is caused by a mutation on the NOTCH3 gene. The pathological driver behind this disease is the loss of vascular smooth muscle cells (VSMCs) in small blood vessels and subsequent fibrotic thickening of the vessel, causing stenosis. LÄS MER
5. Vascular dementia - classification and clinical correlates
Sammanfattning : During the period (1976-1995) a total of 175 consecutive patients (m 88/f 87) with neuropathologically verified vascular dementia (VaD) were examined. 22 patients with pure Alzheimer's Disease (AD) were also studied. All patients were diagnosed and followed at the Department of Psychogeriatrics (Lund University Hospital). LÄS MER