Sökning: "small chromosomes"
Visar resultat 1 - 5 av 42 avhandlingar innehållade orden small chromosomes.
1. Profiling of Small Intestine Neuroendocrine Tumors
Sammanfattning : Small intestine neuroendocrine tumors (SI-NETs) are malignant neoplasms usually presenting with disseminated disease and symptoms of hormone overproduction. Radical surgery is curative but can only be performed for localized disease. For most patients the disease follows a progressive and fatal course. LÄS MER
2. Genome dynamics and virulence in the human pathogen Candida glabrata
Sammanfattning : Although the yeast Candida glabrata is considered to be a part of the commensal microflora in healthy individuals, during the last years it has been frequently isolated from patients with mucosal and systemic fungal infections. Now it is considered as the second most frequently isolated pathogenic yeast after Candida albicans. Despite its name, C. LÄS MER
3. Structural chromosomal aberrations and neuropsychiatric disorders
Sammanfattning : Infantile autism (IA) is a severe neurodevelopment disorder with a complex genetic predisposition. The underlying causes of autism are still not understood. LÄS MER
4. The genetic architecture of sexual dimorphism
Sammanfattning : Phenotypic differences between the sexes evolve largely because selection favours a different complement of traits in either sex. Theory suggests that, despite its frequency, sexual dimorphism should be generally constrained from evolving because the sexes share much of their genome. LÄS MER
5. Molecular aspects of tumor development and treatment for small intestinal neuroendocrine tumors
Sammanfattning : Small intestinal neuroendocrine tumors (SI-NETs) may cause symptoms due to excess secretion of hormones and peptides. The molecular mechanisms behind development of SINETs are not well understood. Copy number alterations, especially loss of chromosome 18q, have been reported and recently p27 mutations were implicated in SI-NET tumorigenesis. LÄS MER