Sökning: "malaria infection"
Visar resultat 1 - 5 av 92 avhandlingar innehållade orden malaria infection.
1. Genetic analysis of murine malaria
Sammanfattning : Malaria, an infectious disease caused by Plasmodium parasites, is one of the major world-scale health problems. Despite the efforts aimed at finding an effective way to control the disease, the success has been thwarted by the emergence of parasite drug resistance and mosquito resistance to insecticides. LÄS MER
2. Aspects of infection and leukemia in Rwanda
Sammanfattning : A first part of this thesis addressed the potential impact of variants of genes encoding interferon-λ4, which is a cytokine that participates in protection against pathogens at epithelial surfaces, for the resolution of upper respiratory tract infections in Rwandan children. In a study of 480 subjects (≤5 years old), where follow-up samples were available from 161 subjects, it was observed that IFNL4 genotypes were associated with clearance of RNA viruses from upper airways. LÄS MER
3. Studies on malaria blood stage infection and host responses
Sammanfattning : The challenges in controlling malaria infectious disease are increasing due to drug resistance and incomplete immunity induced by malaria infection. Moreover there is no effective vaccine available against malaria blood stage infection. LÄS MER
4. Host responses to malaria and bacterial co-infections
Sammanfattning : The two main causes of child mortality and morbidity in Africa are malaria and invasive bacterial diseases. In addition, co-infections in sub-Saharan Africa are the rule rather than the exception. However, not much is known about the host-pathogen interaction during a concomitant infection or how it affects the outcome of disease. LÄS MER
5. Malaria and relapsing fever Borrelia : interactions and potential therapy
Sammanfattning : Infectious diseases such as malaria and relapsing fever borreliosis (RF), cause severe human mortality and morbidity in developing countries. Malaria, caused by Plasmodium spp. parasites, is estimated by the World Health Organization to cause 1.5-2. LÄS MER