Sökning: "kallikrein"

Visar resultat 11 - 15 av 30 avhandlingar innehållade ordet kallikrein.

  1. 11. Studies on the fibrinolytic and kallikrein-kinin systems with special reference to thromboembolism : experimental, clinical and autopsy investigations

    Författare :Mats Eriksson; Uppsala universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : .... LÄS MER

  3. 12. Mechanism and therapy of hereditary angioedema typ III and role of the contact system in inflammatory diseases

    Författare :Jenny Björkqvist; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Combinations of proinflammatory and procoagulant reactions are associated with a variety of disorders affecting the cardiovascular system. Vascular leakage contributes to the pathology of conditions such as, sepsis, allergy and anaphylactic reactions. LÄS MER

  4. 13. Streptococcal virulence and the coagulation system

    Författare :Kristofer Wollein Waldetoft; Infektionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Streptococci; virulence; coagulation; intrinsic pathway; evolution;

    Sammanfattning : This thesis explores streptococcal virulence from both mechanistic and evolutionary perspectives, where the mechanistic studies focus on interactions with the human coagulation system. We describe interactions between streptococcal surface proteins and components of the intrinsic pathway of coagulation and the kallikrein-kinin system in human plasma, as well as to how these surface proteins are produced in different growth phases. LÄS MER

  5. 14. Predicting prostate cancer : on the use of biomarkers in prostate cancer diagnostics

    Författare :Tobias Nordström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Aims: The aims of this thesis work were to answer the following questions. Paper I: How prevalent is testing and retesting with prostate-specific antigen (PSA)?; Paper II: Is a genetic score based on single-nucleotide polymorphisms (SNPs) informative regarding the risk of prostate cancer (PCa) in men with low PSA?; Paper III: Are the commercially available tests Prostate Health Index (PHI) and the four-kallikrein panel comparable in aiding biopsy decisions?; Paper IV: Do commonly used medications affect PSA and the risk of PCa? Methods: In Paper I and Paper IV, the population-based PSA cohort STHLM0 was used together with registry-based data. LÄS MER

  7. 15. Endothelial Barrier Dysfunction in Multiple Organ Injury. An Experimental Study in Rats

    Författare :Xiaoming Deng; Lund Kirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; orthopaedics; Surgery; Endothelial barrier permeability; Multiple organ dysfunction syndrome; Zymosan; traumatology; Kirurgi; ortopedi; traumatologi;

    Sammanfattning : Multiple organ dysfunction syndrome (MODS) is still the leading cause of mortality in the surgical intensive care unit. The effect on among others endothelial barrier permeability, reticuloendothelial function, organ function and protease-antiprotease activities was studied following a variety of challenges, especially over-activation of macrophages induced by intraperitoneal administration of zymosan. LÄS MER